Searching journal content for articles similar to Magrini et al. 14 (8): 1603.

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  1. ...contributed equally to this work. Corresponding authors: thomas.near@yale.edu, clad@ihb.ac.cn, yangliandong1987@163.comAbstractGenomic evolution can propel and restrict species diversification. Rapid molecular evolution and genomic rearrangement is often associated with increased species diversification...
  2. ...of Medicine, Stanford University, Stanford, California 94305, USA; 3Department of Applied Physics, Stanford University, Stanford, California 94305, USA; 4Center for Personal Dynamic Regulomes, Stanford University, Stanford, California 94305, USA; 5Chan Zuckerberg Biohub, San Francisco, California 94158, USA...
  3. ...@tamu.edu, jje@uci.eduAbstractMany essential functions of organisms are encoded in highly repetitive genomic regions, including histones involved in DNA packaging, centromeres that are core components of chromosome segregation, ribosomal RNA comprising the protein translation machinery, telomeres that ensure...
  4. ...develop a dynamic barrier model, where CTCF sites switch between bound and unbound states. Using this model, we investigate how barrier dynamics would impact observables for a range of experimental genomic and imaging data sets, including ChIP-seq, Hi-C, and microscopy. We find the interplay of CTCF...
  5. ...: chirag@iisc.ac.inAbstractAffordable genotyping methods are essential in genomics. Commonly used genotyping methods primarily support single-nucleotide variants and short indels but neglect structural variants. Additionally, accuracy of read alignments to a reference is unreliable in highly polymorphic...
  6. ...fission, leaving the main cluster on Chr 1 and duplicated genes on Chr 2.Given the critical dependence of Hox gene regulation on genomic organization, we hypothesized that physical separation might alter gene expression. To investigate this, we analyzed the expression of bryozoan Hox paralogs located...
  7. ...1977). The presence of a nucleosome alters DNA's geometry and physically shields it, affecting interactions with other DNA-binding proteins (Piña et al. 1990; Pryciak and Varmus 1992; Morgunova and Taipale 2021). The nucleosome thus participates in and regulates numerous molecular processes (Campos...
  8. ...and Jonas Paulsen1 1Department of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo, 0316 Oslo, Norway; 2Department of Genome Sciences, The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory 2601, Australia; 3...
  9. .... 2013), including mitochondrial dysfunction, genomic instability, and cellular senescence. The stochastic development of mtDNA deletion mutations has implications for the role of these mutations in somatic mosaicism (Campbell et al. 2015) and aging in postmitotic tissues. The relative lack of genetic...
  10. ..., Victoria 3065, Australia; 19Molecular Medicine Laboratory and Neurology Department, Concord Repatriation General Hospital, Concord, New South Wales 2139, Australia; 20Faculty of Medicine and Health, The University of Sydney, Camperdown, New South Wales 2050, Australia; 21Genomics and Inherited Disease...
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