Searching journal content for articles similar to Lu et al. 28 (9): 1309.

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  1. Perspective: Gene regulatory networks and the role of robustness and stochasticity in the control of gene expression
    • Lesley T. MacNeil and
    • Albertha J.M. Walhout
    Genome Res. May 2011 21: 645-657; Published in Advance February 4, 2011, doi:10.1101/gr.097378.109
    ...of their downstream targets. Other regulators of gene expression include transcriptional cofactors that can physically interact with TFs, chromatin or components of the basal transcriptional machinery; RNA binding proteins that interact with mRNAs and regulate translation or mRNA stability; and microRNAs that repress...
  2. Research: Dosage-sensitive functions in embryonic development drove the survival of genes on sex-specific chromosomes in snakes, birds, and mammals
    • Daniel W. Bellott and
    • David C. Page
    Genome Res. February 2021 31: 198-210; Published in Advance January 21, 2021, doi:10.1101/gr.268516.120
    ...of duplication (Fig. 2C). MicroRNAs (miRNAs) are short, noncoding RNAs that fine-tune gene dosage by pairing to the 3′ untranslated region and lowering target mRNA levels (Bartel 2009). Conserved targeting by miRNAs is a feature of genes sensitive to changes in gene dosage, particularly to overexpression (Naqvi...
  3. Perspective: Evolution under canalization and the dual roles of microRNAs—A hypothesis
    • Chung-I Wu,
    • Yang Shen,
    • and Tian Tang
    Genome Res. May 2009 19: 734-743; doi:10.1101/gr.084640.108
    ...can evolve gradually in complex regulatory gene networks with varying topology. PLoS Comput. Biol. 3: 164–173. Cohen, S.M., Brennecke, J., and Stark, A. 2006. Denoising feedback loops by thresholding—a new role for microRNAs. Genes & Dev. 20: 2769– 2772. Cui, Q., Yu, Z., Purisima, E.O., and Wang, E...
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