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  1. ...or to discriminate species-specific differences in leaky expression from tissue- and developmental-stage-specific variation. Information concerning molecular mechanisms of marsupial pXCI is also rudimentary. To date, single-gene bisulfite sequencing of CpG islands around selected X-linked genes has identified...
  2. ...+C content through a general GC to AT mutation bias, with methylated cytosines in CpG dinucleotides especially prone to mutation through deamination to thymine. In the absence of an opposing process, such as selection at specific sites, this mutational bias should lead to the inexorable decline of G...
  3. ...differences between males and females of female heterogametic taxa are scarce.Nevertheless, several previous studies have suggested a potential role for DNA methylation in avian sex chromosome regulation. For example, the distribution of CpG islands has been shown to have a significant impact on Z-linked gene...
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