Searching journal content for articles similar to Liu et al. 28 (7): 998.

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  1. ...detection of repeat counts combined with methylation over AR or RP2 CpG islands (Johansson et al. 2023) or even using chromatin accessibility (Lee et al. 2020; Vollger et al. 2025).Long cell-free DNACell-free DNA (cfDNA) fragments circulating in bodily fluids like plasma and urine carry unique methylation...
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  2. ...Corrigendum: Inherited DNA methylation primes the establishment of accessible chromatin during activation Guifen Liu, Wen Wang, Shengen Hu, Xiangxiu Wang and Yong Zhang Genome Research 28: 998–1007 (2018)In the above-mentioned article, two supplemental tables contained errors that have now been...
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  3. ...the 0% or 100% methylation expected at imprinting control regions in germline samples. In contrast, the small fraction of GC-methylated reads, reflecting accessible cell-free chromatin, includes a mix of methylated and unmethylated ICRs consistent with a somatic origin for these DNA molecules. (C) ATAC...
  4. ..., nucleosome positioning, and chromatin binding of the architectural protein CTCF play an important role for establishing cell-type–specific chromatin states during differentiation. To elucidate molecular mechanisms that link these processes, we studied the perturbed DNA modification landscape in mouse...
  5. ...of a genomic boundary element (Darrow and Chadwick 2014). We also observed methylation gradients at the two ends of the Chr 1 5S rDNA cluster with of repeating 2.2 kb 5S-rRNA repeat, although in this case, the gradients were asymmetric. Several regions of the 45S rDNA clusters were in this extreme CpG density...
  6. ..., USA ↵8 These authors contributed equally to this work. ↵9 These authors contributed equally to this work. Corresponding author: john.wiencke@ucsf.eduAbstractStem cell maturation is a fundamental, yet poorly understood aspect of human development. We devised a DNA methylation signature deeply...
  7. ...and developmental promoters and enhancers in zebrafish sperm lack DNA methylation and contain H3K4me3, H2A.Z/FV, H3K27ac, and (at developmental genes) H3K27me3 (Wu et al. 2011; Murphy et al. 2018; Zhang et al. 2018). Additionally, histone chromatin marks and DNA methylation are reprogrammed during pre-ZGA zebrafish...
  8. ...mechanisms are implemented in different animals.The basic units of chromatin structure are the nucleosomes, which restrict the in vivo access of most TFs to their target sites (Beato and Eisfeld 1997; Luo et al. 2014). Although many TFs cannot bind their target site in the context of nucleosome DNA in vitro...
  9. ...Chase, Maryland 20815, USA; 7Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge CB2 0RE, United Kingdom; 8The New York Genome Center, New York, New York 10013, USA Corresponding author: andrewds@usc.eduAbstractDNA methylation in the germline is among the most...
  10. ...research resources is a big challenge.The ENCODE Consortium uses a set of genomic assays as the standard, including DNA binding (ChIP-seq for histones and TFs), DNA accessibility (ATAC-seq, DNase-seq), DNA methylation (WGBS), 3D chromatin structure (ChIA-PET, Hi-C), transcription (bulk RNA-seq, long read...
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