Searching journal content for articles similar to Lin et al. 34 (2): 310.

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  1. ...provide the diploid chromatin architecture for understanding the parent-of-origin effects and the regulation (e.g., cis- or trans-acting regulatory variation) of allele-specific expression (ASE) between homologous chromosomes. Additionally, haplotype-resolved diploid s of the F1-hybrid will help...
  2. ...species based on the creation of high-quality complete assemblies of representatives of as many existing breeds as practical. Members of the consortium have applied the trio binning approach (Koren et al. 2018) to improve efficiency and have generated highly contiguous, haplotype-resolved assemblies...
  3. ...of TEs on expression of nearby genes are to be interpreted with caution.To circumvent the above-mentioned reference bias for insertion–deletion polymorphisms, future studies of TE activity will require a data set combining transcriptome data with haplotype-resolved de novo assemblies for all individuals...
  4. ...by fluorescence in situ hybridization (FISH) in the same Macaca mulatta individual (MMU1) for which Strand-seq data were generated. To also define if an inversion was polymorphic, 14 inversions were tested on two additional macaque individuals (M. mulatta, MMU2; Macaca fascicularis, MFA63). Owing to technical...
  5. ...the potential to dramatically improve medicine, agriculture, biotechnology, and our fundamental understanding of living systems. Recent advances have generated extensive annotation of genomic and epigenomic regulatory modules within chromatin (Bernstein et al. 2010; The ENCODE Project Consortium 2012; Roadmap...
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