Searching journal content for articles similar to Liang et al. 23 (4): 716.

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  1. Review: A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest
    • Andrew D. Bates,
    • Dawid Grzela,
    • Maciej Studzian,
    • Louise Brennan,
    • Moli Williams,
    • Conor Fawcett,
    • Beth Hammond,
    • Manreen Grewal,
    • Marcin Ratajewski,
    • Lukasz Pulaski,
    • and Urszula L. McClurg
    Genome Res. March 2026 36: 433-459; Published in Advance February 17, 2026, doi:10.1101/gr.281154.125
    ...sequences and their association with expression quantitative trait loci (eQTLs) to form the most comprehensive resource of this type, accessible through the UCSC Genome Browser. If your GOI and/or candidate TF are known to be expressed in human cancer, two useful tools that are relevant are DepMap, which...
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  2. Research: Genome-wide evaluation of the effect of short tandem repeat variation on local DNA methylation
    • Alejandro Martin-Trujillo,
    • Paras Garg,
    • Nihir Patel,
    • Bharati Jadhav,
    • and Andrew J. Sharp
    Genome Res. February 2023 33: 184-196; Published in Advance December 28, 2022, doi:10.1101/gr.277057.122
    ...of quantitative trait loci (QTLs) often allows characterization of the functional consequences of sequence variation on gene expression (eQTLs) (Dixon et al. 2007; Göring et al. 2007; Stranger et al. 2007), DNA methylation (mQTLs) (Martin-Trujillo et al. 2020; Villicaña and Bell 2021), histone modifications (Mc...
  3. Perspective: Genomic approaches for understanding the genetics of complex disease
    • William L. Lowe, Jr. and
    • Timothy E. Reddy
    Genome Res. October 2015 25: 1432-1441; doi:10.1101/gr.190603.115
    ...in a phenotype-associated locus are needed. Genetic associations with gene expression reveal target genes Studies to associate genetic variants with gene expression have generated extensive catalogs of expression quantitative trait loci (eQTLs) in diverse cell types and conditions (e.g., Gamazon et al. 2010...
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  4. Research: Characterizing the genetic basis of transcriptome diversity through RNA-sequencing of 922 individuals
    • Alexis Battle,
    • Sara Mostafavi,
    • Xiaowei Zhu,
    • James B. Potash,
    • Myrna M. Weissman,
    • Courtney McCormick,
    • Christian D. Haudenschild,
    • Kenneth B. Beckman,
    • Jianxin Shi,
    • Rui Mei,
    • Alexander E. Urban,
    • Stephen B. Montgomery,
    • Douglas F. Levinson,
    • and Daphne Koller
    Genome Res. January 2014 24: 14-24; Published in Advance October 3, 2013, doi:10.1101/gr.155192.113
    ...of genetic variation with expression (Goring et al. 2007; Stranger et al. 2007), revealing expression quantitative trait loci (eQTLs) in a variety of populations, tissues, and contexts (Dimas et al. 2009; Grundberg et al. 2012; Stranger et al. 2012; Liang et al. 2013).Many genetic variants shown to have...
  5. Research: Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex
    • Claire Vandiedonck,
    • Martin S. Taylor,
    • Helen E. Lockstone,
    • Katharine Plant,
    • Jennifer M. Taylor,
    • Caroline Durrant,
    • John Broxholme,
    • Benjamin P. Fairfax,
    • and Julian C. Knight
    Genome Res. July 2011 21: 1042-1054; Published in Advance May 31, 2011, doi:10.1101/gr.116681.110
    ...are heritable (Yan et al. 2002) and can bemapped as quantitative traits (Emilsson et al. 2008; Cheung and Spielman 2009). Such studies have already highlighted cis- and trans-acting SNPs within the MHC (Dixon et al. 2007; Vandiedonck andKnight 2009). However, these studies andmore recentRNA-seqbased expression...
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  1. April 2026, 36 (4)
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