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Li et al. 31 (1): 13
.
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Research
:
Transcriptome-wide systematic search does not detect A-to-I RNA editing in
cis
-antisense RNA duplexes
Zohar Rosenwasser
,
Roni Cohen-Fultheim
,
Ofir Shliefer
,
Erez Y. Levanon
,
and
Eli Eisenberg
Genome Res.
March 12, 2026
gr.280820.125
;
Published in Advance
March 12, 2026
,
doi:
10.1101/gr.280820.125
..., catalyzed by the adenosine deaminase acting on
RNA
(ADAR) enzymes, is a posttranscriptional process that modifies
RNA
sequences and diversifies the
transcriptome
. ADARs bind to double-stranded
RNA
(ds
RNA
) and their specificity and efficiency are affected by the structural properties of these substructures...
Abstract
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Research
:
Critical roles of long noncoding RNAs in
Drosophila
spermatogenesis
Kejia Wen
,
Lijuan Yang
,
Tuanlin Xiong
,
Chao Di
,
Danhui Ma
,
Menghua Wu
,
Zhaoyu Xue
,
Xuedi Zhang
,
Li Long
,
Weimin Zhang
,
Jiaying Zhang
,
Xiaolin Bi
,
Junbiao Dai
,
Qiangfeng Zhang
,
Zhi John Lu
,
and
Guanjun Gao
Genome Res.
September 2016
26
:
1233
-
1244
;
Published in Advance
August 11, 2016
,
doi:
10.1101/gr.199547.115
...Critical roles of long
noncoding
RNAs
in Drosophila
spermatogenesis
Kejia Wen 1 , 6 , Lijuan Yang 1 , 2 , 6 , Tuanlin Xiong 1 , 6 , Chao Di 1 , Danhui Ma 1 , Menghua Wu 1 , Zhaoyu Xue 1 , Xuedi Zhang 1...
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:
De novo transcriptome assembly of mouse male germ cells reveals novel genes, stage-specific bidirectional promoter activity, and noncoding RNA expression
Mark E. Gill
,
Alexia Rohmer
,
Serap Erkek-Ozhan
,
Ching-Yeu Liang
,
Sunwoo Chun
,
Evgeniy A. Ozonov
,
and
Antoine H.F.M. Peters
Genome Res.
December 2023
33
:
2060
-
2078
;
Published in Advance
December 21, 2023
,
doi:
10.1101/gr.278060.123
...of repetitive sequences to the spermatogenic
transcriptome
.We set out to create a more complete catalog of genes expressed during postreplicative
spermatogenesis
by isolating several specific cell types, performing a deep-coverage, paired-end
RNA
-seq analysis and generating a de novo annotation for genes...
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Method
:
Accurate assembly of circular RNAs with TERRACE
Tasfia Zahin
,
Qian Shi
,
Xiaofei Carl Zang
,
and
Mingfu Shao
Genome Res.
September 2024
34
:
1365
-
1370
;
Published in Advance
July 26, 2024
,
doi:
10.1101/gr.279106.124
...full-length circular
RNA
isoforms in human
transcriptomes
. Nat Commun 12: 266. doi:10.1038/s41467-020-20459-8 ↵Yang W, Du WW, Li X, Yee AJ, Yang BB. 2016. Foxo3 activity promoted by
non-coding
effects of circular
RNA
and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis. Oncogene 35...
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Research
:
TP53-inducible putative long noncoding RNAs encode functional polypeptides that suppress cell proliferation
Wenli Xu
,
Chang Liu
,
Bing Deng
,
Penghui Lin
,
Zhenghua Sun
,
Anrui Liu
,
Jiajia Xuan
,
Yuying Li
,
Keren Zhou
,
Xiaoqin Zhang
,
Qiaojuan Huang
,
Hui Zhou
,
Qingyu He
,
Bin Li
,
Lianghu Qu
,
and
Jianhua Yang
Genome Res.
June 2022
32
:
1026
-
1041
;
Published in Advance
May 24, 2022
,
doi:
10.1101/gr.275831.121
...-encoded microproteins to the TP53 pathway, leading to a better understanding on the complexity of TP53 regulatory network.View larger version: In this window In a new window Figure 7. The expanded TP53 network. Network of the main TP53-inducible coding and
noncoding
RNAs
in human cells as found in this
screen
. Lnc
RNAs
...
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Method
:
Deep sequencing of short capped RNAs reveals novel families of noncoding RNAs
Michiel de Hoon
,
Alessandro Bonetti
,
Charles Plessy
,
Yoshinari Ando
,
Chung-Chau Hon
,
Yuri Ishizu
,
Masayoshi Itoh
,
Sachi Kato
,
Dongyan Lin
,
Sho Maekawa
,
Mitsuyoshi Murata
,
Hiromi Nishiyori
,
Jay W. Shin
,
Jens Stolte
,
Ana Maria Suzuki
,
Michihira Tagami
,
Hazuki Takahashi
,
Supat Thongjuea
,
Alistair R.R. Forrest
,
Yoshihide Hayashizaki
,
Juha Kere
,
and
Piero Carninci
Genome Res.
September 2022
32
:
1727
-
1735
;
Published in Advance
August 12, 2022
,
doi:
10.1101/gr.276647.122
.... 2012. 5′ End–centered expression profiling using cap-analysis gene expression and next-generation sequencing. Nat Protoc 7: 542–561. doi:10.1038/nprot.2012.005 ↵Uszczynska-Ratajczak B, Lagarde J, Frankish A, Guigó R, Johnson R. 2018. Towards a complete map of the human long
non-coding
RNA
transcriptome
...
Abstract
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Resource
:
Functional annotation of human long noncoding RNAs via molecular phenotyping
Jordan A. Ramilowski
,
Chi Wai Yip
,
Saumya Agrawal
,
Jen-Chien Chang
,
Yari Ciani
,
Ivan V. Kulakovskiy
,
Mickaël Mendez
,
Jasmine Li Ching Ooi
,
John F. Ouyang
,
Nick Parkinson
,
Andreas Petri
,
Leonie Roos
,
Jessica Severin
,
Kayoko Yasuzawa
,
Imad Abugessaisa
,
Altuna Akalin
,
Ivan V. Antonov
,
Erik Arner
,
Alessandro Bonetti
,
Hidemasa Bono
,
Beatrice Borsari
,
Frank Brombacher
,
Christopher J.F. Cameron
,
Carlo Vittorio Cannistraci
,
Ryan Cardenas
,
Melissa Cardon
,
Howard Chang
,
Josée Dostie
,
Luca Ducoli
,
Alexander Favorov
,
Alexandre Fort
,
Diego Garrido
,
Noa Gil
,
Juliette Gimenez
,
Reto Guler
,
Lusy Handoko
,
Jayson Harshbarger
,
Akira Hasegawa
,
Yuki Hasegawa
,
Kosuke Hashimoto
,
Norihito Hayatsu
,
Peter Heutink
,
Tetsuro Hirose
,
Eddie L. Imada
,
Masayoshi Itoh
,
Bogumil Kaczkowski
,
Aditi Kanhere
,
Emily Kawabata
,
Hideya Kawaji
,
Tsugumi Kawashima
,
S. Thomas Kelly
,
Miki Kojima
,
Naoto Kondo
,
Haruhiko Koseki
,
Tsukasa Kouno
,
Anton Kratz
,
Mariola Kurowska-Stolarska
,
Andrew Tae Jun Kwon
,
Jeffrey Leek
,
Andreas Lennartsson
,
Marina Lizio
,
Fernando López-Redondo
,
Joachim Luginbühl
,
Shiori Maeda
,
Vsevolod J. Makeev
,
Luigi Marchionni
,
Yulia A. Medvedeva
,
Aki Minoda
,
Ferenc Müller
,
Manuel Muñoz-Aguirre
,
Mitsuyoshi Murata
,
Hiromi Nishiyori
,
Kazuhiro R. Nitta
,
Shuhei Noguchi
,
Yukihiko Noro
,
Ramil Nurtdinov
,
Yasushi Okazaki
,
Valerio Orlando
,
Denis Paquette
,
Callum J.C. Parr
,
Owen J.L. Rackham
,
Patrizia Rizzu
,
Diego Fernando Sánchez Martinez
,
Albin Sandelin
,
Pillay Sanjana
,
Colin A.M. Semple
,
Youtaro Shibayama
,
Divya M. Sivaraman
,
Takahiro Suzuki
,
Suzannah C. Szumowski
,
Michihira Tagami
,
Martin S. Taylor
,
Chikashi Terao
,
Malte Thodberg
,
Supat Thongjuea
,
Vidisha Tripathi
,
Igor Ulitsky
,
Roberto Verardo
,
Ilya E. Vorontsov
,
Chinatsu Yamamoto
,
Robert S. Young
,
J. Kenneth Baillie
,
Alistair R.R. Forrest
,
Roderic Guigó
,
Michael M. Hoffman
,
Chung Chau Hon
,
Takeya Kasukawa
,
Sakari Kauppinen
,
Juha Kere
,
Boris Lenhard
,
Claudio Schneider
,
Harukazu Suzuki
,
Ken Yagi
,
Michiel J.L. de Hoon
,
Jay W. Shin
,
and
Piero Carninci
Genome Res.
July 2020
30
:
1060
-
1072
;
Published in Advance
July 27, 2020
,
doi:
10.1101/gr.254219.119
...suitable for functional
screenings
of our lnc
RNA
(62% found in the nuclear compartment). Besides, the dynamics of secondary effects mediated by different levels of knockdown from different technologies are likely to be observed as discordance when considering the whole
transcriptome
, where this kind...
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Research
:
tRNA-derived small RNAs are embedded in the gene regulatory network instructing
Drosophila
metamorphosis
Junling Shi
,
Jiaqi Xu
,
Jun Ma
,
and
Feng He
Genome Res.
December 2023
33
:
2119
-
2132
;
Published in Advance
November 16, 2023
,
doi:
10.1101/gr.278128.123
...of Genetics, Zhejiang University International School of Medicine, Hangzhou, Zhejiang 310058, China; 4Zhejiang Provincial Key Laboratory of Genetic and Developmental Disorder, Hangzhou, Zhejiang 310058, China Corresponding authors: jun_ma@zju.edu.cn, feng_he@zju.edu.cnAbstractA class of
noncoding
RNAs
...
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Research
:
Long-read transcriptome sequencing of CLL and MDS patients uncovers molecular effects of
SF3B1
mutations
Alicja Pacholewska
,
Matthias Lienhard
,
Mirko Brüggemann
,
Heike Hänel
,
Lorina Bilalli
,
Anja Königs
,
Felix Heß
,
Kerstin Becker
,
Karl Köhrer
,
Jesko Kaiser
,
Holger Gohlke
,
Norbert Gattermann
,
Michael Hallek
,
Carmen D. Herling
,
Julian König
,
Christina Grimm
,
Ralf Herwig
,
Kathi Zarnack
,
and
Michal R. Schweiger
Genome Res.
November 2024
34
:
1832
-
1848
;
Published in Advance
September 13, 2024
,
doi:
10.1101/gr.279327.124
...) and myelodysplastic syndromes (MDSs). These mutations have different effects on the disease prognosis with beneficial effect in MDS and worse prognosis in CLL patients. A full-length
transcriptome
approach can expand our knowledge on SF3B1 mutation effects on
RNA
splicing and its contribution to patient survival...
Abstract
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Research
:
Histone deacetylases maintain expression of the pluripotent gene network via recruitment of RNA polymerase II to coding and noncoding loci
Richard D.W. Kelly
,
Kristy R. Stengel
,
Aditya Chandru
,
Lyndsey C. Johnson
,
Scott W. Hiebert
,
and
Shaun M. Cowley
Genome Res.
January 2024
34
:
34
-
46
;
Published in Advance
January 30, 2024
,
doi:
10.1101/gr.278050.123
...inhibitor JQ1 (Fig. 4). PRO-seq allows high-resolution mapping of active
RNA
polymerases across the at both coding and
noncoding
regions and provides information on both the abundance and directionality of transcripts. Analysis of the
transcriptome
in LBH589-treated ESCs revealed that the majority of genes...
Abstract
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