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  1. ...et al. 2019; Jiang et al. 2020a), cfDNA tissue-of-origin deconvolution (Li et al. 2023b), and direct methylation analysis in single-molecule real-time (SMRT) sequencing (Tse et al. 2021).An essential component in ML is to find the best model parameters that achieve the desired performance...
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  2. ...DNA methylation patterns (Fig. 4C).These results suggested that distinct and likely biologically relevant forces drive expression of CLT clusters in the different SKCM and UVM subtypes, a notion that was supported by detailed analysis of individual prognostic CLTs. One such example is the [TRPM1]MLT1A...
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