Searching journal content for articles similar to Li et al. 24 (7): 1086.

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  1. ...C. elegans and the fruit fly Drosophila melanogaster were selected for the modENCODE Project in 2007 because of their experimental strengths and prominence as model organisms as well as for their compact, sequenced s, which simplifies the identification of TF binding sites and candidate target genes...
  2. ..., National University of Singapore, Singapore 117599; 7Institute of Zoology, University of Cologne, 50674 Cologne, Germany Drosophila melanogaster is a widely used genetic model organism in developmental biology. While this model organism has been intensively studied at the RNA level, a comprehensive...
  3. ...junction spanning reads in those RNA-seq profiles revealed a much richer set of processed transcripts. Additional RNA-seq data sets, along with cap analysis of gene expression (CAGE-seq) and full-insert cDNA sequencing, have been used to generate the modENCODE D. melanogaster transcriptome annotation...
  4. ...Integrative analysis with ChIP-seq advances the limits of transcript quantification from RNA-seq Peng Liu 1 , Rajendran Sanalkumar 2 , Emery H. Bresnick 2 , Sündüz Keleş 1 , 3 and Colin N. Dewey 1 , 4 1Department...
  5. ...in green and orange, respectively) were considered “fragile” or “resistant.” Jeffers and Lieb 76 Genome Research www..org TFBSs. We collected a set of 35,062 TFBSs bound at any stage of C. elegans development, as identified by TF ChIP-seq from the modENCODE Consortium (Araya et al. 2014). The DNA...
  6. ...Integrative analysis of C. elegans modENCODE ChIP-seq data sets to infer gene regulatory interactions Eric L. Van Nostrand 1 and Stuart K. Kim 2 Department of Genetics and Department of Developmental Biology, Stanford University Medical Center, Stanford...
  7. ...RNA-seq compendium of reproducibly expressed splice junctions in C. elegans, assembled from 1682 publicly available RNA-seq experiments (Tourasse et al. 2017). Each splice junction has an associated percent spliced in (PSI) value, which is a measure of the frequency of each splice junction relative...
  8. ...at physiological levels (DeKoter and Singh 2000; Fernandez et al. 2003). In ENCODE/modENCODE, tagged factors have been used most extensively thus far for C. elegans studies, where factors have been tagged with GFP and shown to complement mutants; six of six tested to date have been found to complement (Zhong...
  9. ...error rates and the relative lack of bioinformatics tools and analysis pipelines designed for long, error-rich reads.In this study, we have generated an atlas of postembryonic transcript structure using dRNA-seq to sequence RNA extracted from the major stages of the C. elegans developmental life cycle...
  10. ...allows us to characterize highly reproducible changes in chromatin accessibility between developmental stages and to identify functional temporal- and tissue-specific novel enhancers in vivo. Our study provides a unique resource for defining C. elegans regulatory regions as well as a guide...
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