Searching journal content for articles similar to Lavedan 8 (9): 871.

Displaying results 1-10 of 22
For checked items
  1. LETTER: Human and Mouse α-Synuclein Genes: Comparative Genomic Sequence Analysis and Identification of a Novel Gene Regulatory Element
    • Jeffrey W. Touchman,
    • Anindya Dehejia,
    • Ornit Chiba-Falek,
    • Deborah E. Cabin,
    • Jody R. Schwartz,
    • Bonnie M. Orrison,
    • Mihael H. Polymeropoulos,
    • and Robert L. Nussbaum
    Genome Res. January 1, 2001 11: 78-86; doi:10.1101/gr.165801
    ...Human and Mouse α-Synuclein Genes: Comparative Genomic Sequence Analysis and Identification of a Novel Gene Regulatory Element Jeffrey W. Touchman 1 , Anindya Dehejia 2 , Ornit Chiba-Falek 3 , Deborah E. Cabin 3 , Jody R. Schwartz 4...
  2. Resource: Single-nucleus multiomic profiling of the aging mouse substantia nigra reveals conserved gene alterations linked to Parkinson's disease
    • Kangli Wang,
    • Weikun Xia,
    • Yingli Gu,
    • Songpeng Zu,
    • Qian Yang,
    • Maria Luisa Amaral,
    • Yaozhi Wang,
    • Allen Wang,
    • Xiang-Dong Fu,
    • William C. Mobley,
    • and Bing Ren
    Genome Res. March 4, 2026 gr.281113.125; Published in Advance March 4, 2026, doi:10.1101/gr.281113.125
    ...and Hsp90ab1, both members of heat-shock protein 90 (HSP90) family 348 involved in protein folding and protein stabilization(Chen et al. 2005), were upregulated in 349 multiple conserved cell types. Dysfunction of HSP90 has been implicated in alpha-synuclein 350 aggregation and PD pathways(Hernandez et al...
    OPEN ACCESS ARTICLEACCEPTED MANUSCRIPT
  3. Method: Inferring disease progression stages in single-cell transcriptomics using a weakly supervised deep learning approach
    • Fabien Wehbe,
    • Levi Adams,
    • Jordan Babadoudou,
    • Samantha Yuen,
    • Yoon-Seong Kim,
    • and Yoshiaki Tanaka
    Genome Res. January 2025 35: 135-146; Published in Advance December 2, 2024, doi:10.1101/gr.278812.123
    ...threshold of disease progression and early-staged/healthy cells. (E) Comparison of synuclein alpha (SNCA) expression across groups that are segregated by supervised (left) or weakly supervised (right) deep learning. (F) Volcano plots showing differential expression between PD progressive and early...
    OPEN ACCESS ARTICLE
  4. Research: Oxygen-induced stress reveals context-specific gene regulatory effects in human brain organoids
    • Benjamin D. Umans and
    • Yoav Gilad
    Genome Res. August 2025 35: 1689-1700; Published in Advance June 2, 2025, doi:10.1101/gr.280219.124
    OPEN ACCESS ARTICLE
  5. Research: Transcriptional programs mediating neuronal toxicity and altered glial–neuronal signaling in a Drosophila knock-in tauopathy model
    • Hassan Bukhari,
    • Vanitha Nithianandam,
    • Rachel A. Battaglia,
    • Anthony Cicalo,
    • Souvarish Sarkar,
    • Aram Comjean,
    • Yanhui Hu,
    • Matthew J. Leventhal,
    • Xianjun Dong,
    • and Mel B. Feany
    Genome Res. April 2024 34: 590-605; Published in Advance April 10, 2024, doi:10.1101/gr.278576.123
    OPEN ACCESS ARTICLE
  6. Research: Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target
    • Myungjin Jo,
    • Ah Young Chung,
    • Nozomu Yachie,
    • Minchul Seo,
    • Hyejin Jeon,
    • Youngpyo Nam,
    • Yeojin Seo,
    • Eunmi Kim,
    • Quan Zhong,
    • Marc Vidal,
    • Hae Chul Park,
    • Frederick P. Roth,
    • and Kyoungho Suk
    Genome Res. September 2017 27: 1487-1500; Published in Advance June 8, 2017, doi:10.1101/gr.211649.116
    ...dismutase (SOD), and synuclein alpha are the pathological hallmarks of neurodegenerative diseases. The cellular mechanism of neurodegenerative diseases such as Parkinson’s disease (Outeiro and Lindquist 2003; Cooper et al. 2006; Chung et al. 2013; Tardiff et al. 2013; Caraveo et al. 2014), Huntington...
    OPEN ACCESS ARTICLE
  7. Method: Debiased personalized gene coexpression networks for population-scale scRNA-seq data
    • Shan Lu and
    • Sunduz Keles
    Genome Res. June 9, 2023 gr.277363.122; Published in Advance June 9, 2023, doi:10.1101/gr.277363.122
    ACCEPTED MANUSCRIPT
  8. Method: High-throughput single-cell functional elucidation of neurodevelopmental disease–associated genes reveals convergent mechanisms altering neuronal differentiation
    • Matthew A. Lalli,
    • Denis Avey,
    • Joseph D. Dougherty,
    • Jeffrey Milbrandt,
    • and Robi D. Mitra
    Genome Res. September 2020 30: 1317-1331; Published in Advance September 4, 2020, doi:10.1101/gr.262295.120
  9. Research: Identification of FMR1-regulated molecular networks in human neurodevelopment
    • Meng Li,
    • Junha Shin,
    • Ryan D. Risgaard,
    • Molly J. Parries,
    • Jianyi Wang,
    • Deborah Chasman,
    • Shuang Liu,
    • Sushmita Roy,
    • Anita Bhattacharyya,
    • and Xinyu Zhao
    Genome Res. March 2020 30: 361-374; Published in Advance March 16, 2020, doi:10.1101/gr.251405.119
  10. Resource: Global networks of functional coupling in eukaryotes from comprehensive data integration
    • Andrey Alexeyenko and
    • Erik L.L. Sonnhammer
    Genome Res. June 2009 19: 1107-1116; Published in Advance February 25, 2009, doi:10.1101/gr.087528.108
    ...) and yeast ( right , squares). Novel candidates were extracted by looking for human genes that were coupled both to known PD genes and to orthologs of yeast alpha-synuclein toxicity modifiers. This resulted in 12 novel candidate PD genes (red circles). PD and alpha-synuclein toxicity modifier genes...
For checked items

Search Results

Next 10 » New Search

Modify Results

Citation format:
Results / page:
Results order:

This search

  • Alert me when new articles matching this search are published
  • Download all citations on this page to my citation manager

Preprint Server



Current Issue

  1. March 2026, 36 (3)
  1. Current Issue
  1. Alert me to new issues of Genome Research