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METHODS: Fluorescence Polarization in Homogeneous Nucleic Acid Analysis
- Xiangning Chen,
- Leanna Levine,
- and Pui-Yan Kwok
Genome Res. May 1, 1999 9: 492-498; doi:10.1101/gr.9.5.492
...Fluorescence Polarization in Homogeneous Nucleic Acid Analysis Xiangning Chen 1 , 3 , Leanna Levine 2 , and Pui-Yan Kwok 1 1Division of Dermatology and Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110...
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METHODS: Homogeneous Assays for Single-Nucleotide Polymorphism Typing Using AlphaScreen
- Lucille Beaudet,
- Julie Bédard,
- Billy Breton,
- Roberto J. Mercuri,
- and Marcia L. Budarf
Genome Res. April 1, 2001 11: 600-608; doi:10.1101/gr.1725501
.... Genome Res. 10 : 549 – 557 . ↵ Chen X. , Levine L. , Kwok P.Y. ( 1999 ) Fluorescence polarization in homogeneous nucleic acid analysis. Genome Res. 9 : 492 – 498 . ↵ Corder E.H. , Saunders A.M. , Strittmatter W.J. , Schmechel D.E. , Gaskell P.C. , Small G.W. , Roses A.D. , Haines J.L. , Pericak-Vance M...
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METHODS: DNA Analysis by Fluorescence Quenching Detection
- Ming Xiao and
- Pui-Yan Kwok
Genome Res. May 1, 2003 13: 932-939; doi:10.1101/gr.987803
..., , 468–470. . ↵ Chen X. , Levine L. , Kwok P.Y. ( 1999 ) Fluorescence polarization in homogeneous nucleic acid analysis. Genome Res. 9 : 492 – 498 . ↵ Germer S. , Holland M.J. , Higuchi R. ( 2000 ) High-throughput SNP allele-frequency determination in pooled DNA samples by kinetic PCR. Genome Res. 10...
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METHODS: A Novel Method for SNP Detection Using a New Duplex-Specific Nuclease From Crab Hepatopancreas
- Dmitry A. Shagin,
- Denis V. Rebrikov,
- Valery B. Kozhemyako,
- Ilia M. Altshuler,
- Alex S. Shcheglov,
- Pavel A. Zhulidov,
- Ekaterina A. Bogdanova,
- Dmitry B. Staroverov,
- Valery A. Rasskazov,
- and Sergey Lukyanov
Genome Res. December 1, 2002 12: 1935-1942; doi:10.1101/gr.547002
...enzymes used widely in biomedical and biotechnological applications. Their application depends on the specificity and mode of action of a particular enzyme. Nucleases have been employed in the production of flavor enhancers, removal of nucleic acids, as therapeutic agents, and for the determination...
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Research: Cell-type- and chromosome-specific chromatin landscapes and DNA replication programs of Drosophila testis tumor stem cell–like cells
- Jennifer A. Urban,
- Daniel Ringwalt,
- John M. Urban,
- Wingel Xue,
- Ryan Gleason,
- Keji Zhao,
- and Xin Chen
Genome Res. January 2026 36: 83-101; Published in Advance December 10, 2025, doi:10.1101/gr.280809.125
...regulators in GSC-like cells. To characterize chromatin landscapes, we develop a cell-type-specific chromatin profiling assay to map H3K4me3-, H3K27me3-, and H3K9me3-enriched regions, corresponding to the euchromatic, facultative heterochromatic, and constitutive heterochromatic domains, respectively...
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METHODS: Exo-Proofreading, A Versatile SNP Scoring Technology
- Patrick Cahill,
- Michele Bakis,
- James Hurley,
- Veena Kamath,
- William Nielsen,
- Dina Weymouth,
- Josée Dupuis,
- Lynn Doucette-Stamm,
- and Douglas R. Smith
Genome Res. May 1, 2003 13: 925-931; Published in Advance April 14, 2003, doi:10.1101/gr.939903
...: 18 – 23 . ↵ Chen X. , Levine L. , Kwok P.Y. ( 1999 ) Fluorescence polarization in homogeneous nucleic acid analysis. Genome Res. 9 : 492 – 498 . ↵ Chetverin A.B. , Kramer F.R. ( 1993 ) Sequencing of pools of nucleic acids on oligonucleotide arrays. Biosystems 30 : 215 – 231 . ↵ Cline J. , Braman J...
REVIEW: Issues of variability, carryover contamination, and detection in 3SR-based assays.
- E Fahy,
- M Biery,
- M Goulden,
- S S Ghosh,
- and T R Gingeras
Genome Res. April 1994 3: S83-S94
...amplification and time resolved fluorescence detection. Mol. Cell Probes 5 : 467 – 472 . 16.. Devlin, R., , Studholme, R.M. , Dandliker, W.B. , Fahy, E. , Blumeyer, K. , Ghosh. S.S. Devlin, R., Studholme, R.M. Dandliker, W.B. Fahy, E. Blumeyer, K. and Ghosh. S.S. 1993 . Homogeneous detection of nucleic acids...
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METHODS: A Human Genomic Library Enriched in Transcriptionally Active Sequences (aDNA Library)
- Anna L. Pelling,
- Alan W. Thorne,
- and Colyn Crane-Robinson
Genome Res. June 1, 2000 10: 874-886; doi:10.1101/gr.10.6.874
...%) contained highly repeated sequences, as determined by their hybridization to total genomic DNA, and were not analyzed further. An additional 10 clones (6%) were shown to contain no insert DNA. The remaining 146 were sequenced and compared with the nucleic acid databases and in all six frames to the protein...
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ARTICLE: CAGGG Repeats and the Pericentromeric Duplication of the Hominoid Genome
- Evan E. Eichler,
- Nicoletta Archidiacono,
- and Mariano Rocchi
Genome Res. November 1, 1999 9: 1048-1058; doi:10.1101/gr.9.11.1048
...regions 12p11 and 12p13: Similarity between parts of these genes and conserved human telomeric-associated DNA. Genomics 32 : 260 – 265 . ↵ Borden P. , Jaenichen R. , Zachau H. ( 1990 ) Structural features of transposed human Vk genes and implications for the mechanism of their transpositions. Nucleic...

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