Searching journal content for articles similar to Lancaster et al. 29 (10): 1685.

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  1. Research: Improved redox homeostasis owing to the up-regulation of one-carbon metabolism and related pathways is crucial for yeast heterosis at high temperature
    • Liang Song,
    • Jun-Yan Shi,
    • Shou-Fu Duan,
    • Da-Yong Han,
    • Kuan Li,
    • Ri-Peng Zhang,
    • Peng-Yu He,
    • Pei-Jie Han,
    • Qi-Ming Wang,
    • and Feng-Yan Bai
    Genome Res. April 2021 31: 622-634; Published in Advance March 15, 2021, doi:10.1101/gr.262055.120
    ..., despite extensive studies on the phenomenon for more than a century. Here we constructed a large collection of F1 hybrids of Saccharomyces cerevisiae by spore-to-spore mating between homozygous wild strains of the species with different genetic distances and compared growth performance of the F1 hybrids...
  2. Research: Different trajectories of polyploidization shape the genomic landscape of the Brettanomyces bruxellensis yeast species
    • Chris Eberlein,
    • Omar Abou Saada,
    • Anne Friedrich,
    • Warren Albertin,
    • and Joseph Schacherer
    Genome Res. December 2021 31: 2316-2326; Published in Advance November 23, 2021, doi:10.1101/gr.275380.121
    .... 2012; Bertier et al. 2013; Morrow and Fraser 2013; Van de Peer et al. 2017). In the lineage leading to Saccharomyces cerevisiae, a hybridization event between two ancestral species has been followed by subsequent WGD, a means by which, in the subsequent process of extensive reorganization, high...
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  3. Research: Global deceleration of gene evolution following recent genome hybridizations in fungi
    • Sira Sriswasdi,
    • Masako Takashima,
    • Ri-ichiroh Manabe,
    • Moriya Ohkuma,
    • Takashi Sugita,
    • and Wataru Iwasaki
    Genome Res. August 2016 26: 1081-1090; Published in Advance July 20, 2016, doi:10.1101/gr.205948.116
    ...). Nonetheless, although these studies established long-term benefits of polyploidization, early consequences and mechanisms of polyploidization remain largely unexplored. Genome hybridization, in contrast to WGD, which is a rare event, is estimated to occur in >25% of plant and 10% of animal species (Mallet...
  4. Research: Shifts in the intensity of purifying selection: An analysis of genome-wide polymorphism data from two closely related yeast species
    • Eyal Elyashiv,
    • Kevin Bullaughey,
    • Shmuel Sattath,
    • Yosef Rinott,
    • Molly Przeworski,
    • and Guy Sella
    Genome Res. November 2010 20: 1558-1573; Published in Advance September 4, 2010, doi:10.1101/gr.108993.110
    ...and species? How uniform are the shifts in selective pressures across the genome? To address these questions, we took advantage of a recent, whole-genome polymorphism data set from two closely related species of yeast, Saccharomyces cerevisiae and S. paradoxus , paying close attention to the population...
  5. LETTER: Predicting Human Minisatellite Polymorphism
    • France Denoeud,
    • Gilles Vergnaud,
    • and Gary Benson
    Genome Res. May 1, 2003 13: 856-867; Published in Advance April 14, 2003, doi:10.1101/gr.574403
    ...measure, termed HistoryR, based on the presence of variant motifs in the tandem array. We find that HistoryR and percentage of GC are strongly correlated with polymorphism and, as predictive criteria, reduce by half the number of repeats to type while enriching the proportion with heterozygosity ≥0...
  6. Research: Candida albicans isolates contain frequent heterozygous structural variants and transposable elements within genes and centromeres
    • Ursula Oggenfuss,
    • Robert T. Todd,
    • Natthapon Soisangwan,
    • Bailey Kemp,
    • Alison Guyer,
    • Annette Beach,
    • and Anna Selmecki
    Genome Res. April 2025 35: 824-838; Published in Advance October 22, 2024, doi:10.1101/gr.279301.124
    ...of drug efflux pumps (Vanden Bossche et al. 1994; White et al. 1998; Selmecki et al. 2008). Recently, we identified an isochromosome that contains two copies of the right arm of Chr 4, i(4R), that also provides a fitness benefit in the presence of azole drugs (Todd et al. 2019). These isochromosomes arise...
  7. Research: Causes and consequences of a complex recombinational landscape in the ant Cardiocondyla obscurior
    • Mohammed Errbii,
    • Jürgen Gadau,
    • Kerstin Becker,
    • Lukas Schrader,
    • and Jan Oettler
    Genome Res. June 2024 34: 863-876; Published in Advance June 5, 2024, doi:10.1101/gr.278392.123
    .... obscurior is a highly inbred tramp species and its populations experience genetic bottlenecks, reducing diversity in this species (Heinze 2017). Along with genetic hybridization and an increased TE activity (Errbii et al. 2021), introduced populations of this species may benefit from the effects...
  8. METHODS: Whole Genome Analysis of Genetic Alterations in Small DNA Samples Using Hyperbranched Strand Displacement Amplification and Array–CGH
    • José M. Lage,
    • John H. Leamon,
    • Tanja Pejovic,
    • Stefan Hamann,
    • Michelle Lacey,
    • Deborah Dillon,
    • Richard Segraves,
    • Bettina Vossbrinck,
    • Antonio González,
    • Daniel Pinkel,
    • Donna G. Albertson,
    • Jose Costa,
    • and Paul M. Lizardi
    Genome Res. February 1, 2003 13: 294-307; doi:10.1101/gr.377203
    ...mechanism, and generate hundreds, or even thousands, of copies of the genome in a few hours. Using whole genome isothermal amplification, in combination with comparative genomic hybridization on cDNA microarrays, we demonstrate the ability to detect gene losses in yeast and gene dosage imbalances in human...
  9. METHODS: A Microsphere-Based Assay for Multiplexed Single Nucleotide Polymorphism Analysis Using Single Base Chain Extension
    • Jingwen Chen,
    • Marie A. Iannone,
    • May-Sung Li,
    • J. David Taylor,
    • Philip Rivers,
    • Anita J. Nelsen,
    • Kimberly A. Slentz-Kesler,
    • Allen Roses,
    • and Michael P. Weiner
    Genome Res. April 1, 2000 10: 549-557; doi:10.1101/gr.10.4.549
    ...the reaction products for analysis, the ZipCode portion of the oligonucleotide was hybridized with its cZipCodes on the microsphere. Flow cytometry was used for microsphere decoding and SNP typing by detecting the fluorescein label captured on the microspheres. In addition to multiplexing capability, the Zip...
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