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Laan et al. 5 (1): 13
.
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Method
:
High-resolution genotype-free mapping of genetic variation with CRI-SPA-Map
Sheila Lutz
,
Megan Lawler
,
Samuel Amidon
,
and
Frank W Albert
Genome Res.
March 23, 2026
gr.281514.125
;
Published in Advance
March 23, 2026
,
doi:
10.1101/gr.281514.125
...in regions that are hard to genotype, such as 415 repetitive regions of the . Second, CRI-SPA-Map has
high
resolution
due to short 416 introduced donor DNA tracts in local isolates and tracts that terminate near the
targeted
ORF in 417 distal isolates. Resolution can be further increased by
targeting
...
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Method
:
High-resolution simulations of chromatin folding at genomic rearrangements in malignant B cells provide mechanistic insights into proto-oncogene deregulation
Daniel Rico
,
Daniel Kent
,
Nefeli Karataraki
,
Aneta Mikulasova
,
Rolando Berlinguer-Palmini
,
Brian A. Walker
,
Biola M. Javierre
,
Lisa J. Russell
,
and
Chris A. Brackley
Genome Res.
July 2022
32
:
1355
-
1366
;
Published in Advance
July 21, 2022
,
doi:
10.1101/gr.276028.121
...) (Dixon et al. 2012). These are contiguous
chromosome
regions which show enriched self-interactions and are thought to be associated with cis-regulatory
mechanisms
; they are often bounded by binding sites for the CCCTC-binding factor CTCF (Rao et al. 2014). ChIP-seq profiling of histone modifications...
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Research
:
A high resolution A-to-I editing map in the mouse identifies editing events controlled by pre-mRNA splicing
Konstantin Licht
,
Utkarsh Kapoor
,
Fabian Amman
,
Ernesto Picardi
,
David Martin
,
Prajakta Bajad
,
and
Michael F. Jantsch
Genome Res.
September 2019
29
:
1453
-
1463
;
Published in Advance
August 19, 2019
,
doi:
10.1101/gr.242636.118
...RNA-translation efficiency, or proteins associated with the
targeted
RNAs (Bass 2002; Tajaddod et al. 2015; Nishikura 2016; Licht et al. 2019).A-to-I editing is mediated by adenosine deaminases acting on RNAs (ADARs). In mammals, two catalytically active ADAR enzymes, ADAR (ADAR1) and ADARB1 (ADAR2) are known. Both enzymes...
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Methods
:
High-resolution nucleosome mapping reveals transcription-dependent promoter packaging
Assaf Weiner
,
Amanda Hughes
,
Moran Yassour
,
Oliver J. Rando
,
and
Nir Friedman
Genome Res.
January 2010
20
:
90
-
100
;
Published in Advance
October 21, 2009
,
doi:
10.1101/gr.098509.109
...
High-resolution
nucleosome mapping reveals transcription-dependent promoter packaging Assaf Weiner 1 , Amanda Hughes 2 , Moran Yassour 1 , 3 , Oliver J. Rando 2 , 5 and Nir Friedman 1 , 4 , 5 1 School of Computer...
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Resource
:
The pig X and Y Chromosomes: structure, sequence, and evolution
Benjamin M. Skinner
,
Carole A. Sargent
,
Carol Churcher
,
Toby Hunt
,
Javier Herrero
,
Jane E. Loveland
,
Matt Dunn
,
Sandra Louzada
,
Beiyuan Fu
,
William Chow
,
James Gilbert
,
Siobhan Austin-Guest
,
Kathryn Beal
,
Denise Carvalho-Silva
,
William Cheng
,
Daria Gordon
,
Darren Grafham
,
Matt Hardy
,
Jo Harley
,
Heidi Hauser
,
Philip Howden
,
Kerstin Howe
,
Kim Lachani
,
Peter J.I. Ellis
,
Daniel Kelly
,
Giselle Kerry
,
James Kerwin
,
Bee Ling Ng
,
Glen Threadgold
,
Thomas Wileman
,
Jonathan M.D. Wood
,
Fengtang Yang
,
Jen Harrow
,
Nabeel A. Affara
,
and
Chris Tyler-Smith
Genome Res.
January 2016
26
:
130
-
139
;
Published in Advance
November 11, 2015
,
doi:
10.1101/gr.188839.114
..., and thereby to reveal
mechanisms
underlying pig X and Y
Chromosome
evolution. Footnotes ↵ 5 Joint first authors [Supplemental material is available for this article.] Article published online before print. Article, supplemental material, and publication date are at http...
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Letter
:
High-resolution analysis of epigenetic changes associated with X inactivation
Hendrik Marks
,
Jennifer C. Chow
,
Sergei Denissov
,
Kees-Jan Françoijs
,
Neil Brockdorff
,
Edith Heard
,
and
Hendrik G. Stunnenberg
Genome Res.
August 2009
19
:
1361
-
1373
;
Published in Advance
July 6, 2009
,
doi:
10.1101/gr.092643.109
...populations and hybridized to the same
high-resolution
microarrays. The genomic region analyzed was a ;15 Mb segment centered around the X-inactivation center (Xic) ( built MM9 95–109 Mb), which represents ;10% of the X
chromosome
. Supplemental Figure S1 and the supporting Supplementalmaterial document...
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Research
:
Human long intrinsically disordered protein regions are frequent targets of positive selection
Arina Afanasyeva
,
Mathias Bockwoldt
,
Christopher R. Cooney
,
Ines Heiland
,
and
Toni I. Gossmann
Genome Res.
July 2018
28
:
975
-
982
;
Published in Advance
June 1, 2018
,
doi:
10.1101/gr.232645.117
...for pmemd simulations included in the AMBER 14 software package (Salomon-Ferrer et al. 2013). A
high-resolution
three-dimensional structure of human interleukin 21 (IL21) resolved by heteronuclear NMR spectroscopy (PDB code: 2OQP) was used (Bondensgaard et al. 2007).Polymorphism statistics, DFE, and Mc...
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LETTER
:
A high-resolution map of nucleosome positioning on a fission yeast centromere
Jun S. Song
,
Xingkun Liu
,
X. Shirley Liu
,
and
Xiangwei He
Genome Res.
July 2008
18
:
1064
-
1072
;
Published in Advance
April 14, 2008
,
doi:
10.1101/gr.075374.107
...A
high-resolution
map of nucleosome positioning on a fission yeast centromere Jun S. Song 1 , 2 , 4 , Xingkun Liu 3 , 4 , X. Shirley Liu 1 , and Xiangwei He 3 , 5 1 Department of Biostatistics and Computational Biology, Dana...
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Methods
:
Genome-wide, high-resolution DNA methylation profiling using bisulfite-mediated cytosine conversion
Jon Reinders
,
Céline Delucinge Vivier
,
Grégory Theiler
,
Didier Chollet
,
Patrick Descombes
,
and
Jerzy Paszkowski
Genome Res.
March 2008
18
:
469
-
476
;
Published in Advance
January 24, 2008
,
doi:
10.1101/gr.7073008
...Genome-wide,
high-resolution
DNA methylation profiling using bisulfite-mediated cytosine conversion Jon Reinders 1 , 3 , Céline Delucinge Vivier 2 , Grégory Theiler 1 , Didier Chollet 2 , Patrick Descombes 2 , and Jerzy Paszkowski 1...
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Method
:
Centromere reference models for human chromosomes X and Y satellite arrays
Karen H. Miga
,
Yulia Newton
,
Miten Jain
,
Nicolas Altemose
,
Huntington F. Willard
,
and
W. James Kent
Genome Res.
April 2014
24
:
697
-
707
;
Published in Advance
February 5, 2014
,
doi:
10.1101/gr.159624.113
...andWillard 1995; Roizès 2006), and in whole- data from diploid s; accordingly, it is difficult to infer the long-range sequence organization and assign sequence variants to a single array. The X and Y
chromosomes
, represented as haploid arrays in the male , offer a unique opportunity a for
high-resolution
...
Abstract
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