Searching journal content for articles similar to L. Strausberg and Levy 17 (7): 965.

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  1. ..., catalyzed by the adenosine deaminase acting on RNA (ADAR) enzymes, is a posttranscriptional process that modifies RNA sequences and diversifies the transcriptome. ADARs bind to double-stranded RNA (dsRNA) and their specificity and efficiency are affected by the structural properties of these substructures...
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  2. ...Genomics and Transcriptomics Laboratory, Biological and Medical Research Center, Heinrich Heine University and West German Genome Center, 40225 Düsseldorf, Germany; 7Cologne Center for Genomics (CCG), Faculty of Medicine, University of Cologne, 50931 Cologne, Germany; 8Institute for Pharmaceutical...
  3. ...signatures of the neuronal cell types in the telencephalon and the timeline of their emergence from larva to adult remain largely undescribed. Using an integrated analysis of single-cell transcriptomes of approximately 64,000 cells obtained from 6-day-postfertilization (dpf), 15-dpf, and adult telencephalon...
  4. ...and interpret the biological significance of the traits used for estimation. Here we present SCALE, a statistical pipeline that quantifies biological aging in different tissues using explainable features learned from literature and single-cell transcriptomic data. Applying SCALE to the “Mouse Aging Cell Atlas...
  5. ...Single-cell transcriptome and meta profiling reveals the genetic basis of rumen functions and convergent developmental patterns in ruminants Juan Deng1,2,7, Ya-Jing Liu1,7, Wen-Tian Wei1, Qi-Xuan Huang1, Li-Ping Zhao3,4, Ling-Yun Luo1, Qi Zhu2, Lin Zhang2, Yuan Chen2, Yan-Ling Ren5, Shan-Gang Jia6...
  6. ...as the major determinants of gene expression profiles in male germ cells, we wondered whether they may serve as alternative promoters driving additional expression of reference transcripts in specific cell types. We thus further compared our de novo transcriptome annotation with GENCODE using gffcompare...
  7. ...for additional sequence analyses of the 3′ splice sites.Age-dependent up-regulation of intron-derived transcripts and noncoding RNAs matches chronological agingWe then investigated whether the rates of age-dependent deregulation of transcriptome were affected by a longevity-promoting regimen, focusing on daf-2...
  8. ...results demonstrate that the FC-R2 gene expression atlas is a reliable and powerful resource for exploring both the coding and noncoding transcriptome, providing compelling evidence and robust support to the notion that lncRNA gene classes, including enhancers and promoters, despite not being yet fully...
  9. ..., preserving the spatial and morphological context of gene expression. Here, we describe expanding the chemistry for the Digital Spatial Profiling platform to quantify whole transcriptomes in human and mouse tissues using a wide range of spatial profiling strategies and sample types. We designed multiplexed...
  10. ...against viruses. Despite its importance, transcriptomic dynamics with fine temporal resolution across the entire digestion cycle have not yet been reported. To fill this gap, we conducted a transcriptomic analysis of A. aegypti female midguts across a 72-h bloodmeal digestion cycle for 11 time points...
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