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Method: Pooled analysis of radiation hybrids identifies loci for growth and drug action in mammalian cells
- Arshad H. Khan,
- Andy Lin,
- Richard T. Wang,
- Joshua S. Bloom,
- Kenneth Lange,
- and Desmond J. Smith
Genome Res. October 2020 30: 1458-1467; Published in Advance September 2, 2020, doi:10.1101/gr.262204.120
.... 1975. Mammalian somatic hybrids and human gene mapping. Ann Intern Med 83: 553–560. doi:10.7326/0003-4819-83-4-553 ↵Kwitek AE, Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, et al. 2004. High-density rat radiation hybrid maps containing over 24...
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Method: A genome-wide map of human genetic interactions inferred from radiation hybrid genotypes
- Andy Lin,
- Richard T. Wang,
- Sangtae Ahn,
- Christopher C. Park,
- and Desmond J. Smith
Genome Res. August 2010 20: 1122-1132; Published in Advance May 27, 2010, doi:10.1101/gr.104216.109
.... Directed mammalian gene regulatory networks using expression and comparative genomic hybridization microarray data from radiation hybrids. PLoS Comput Biol 5: e1000407. doi: 10.1371/ journal.pcbi.1000407. Albert R, Barabasi AL. 2002. Statistical mechanics of complex networks. Rev Mod Phys 74: 47...
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RESEARCH: A High-Density Integrated Genetic Linkage and Radiation Hybrid Map of the Laboratory Rat
- Robert G. Steen,
- Anne E. Kwitek-Black,
- Christopher Glenn,
- Jo Gullings-Handley,
- William Van Etten,
- O. Scott Atkinson,
- Diane Appel,
- Simon Twigger,
- Melanie Muir,
- Tim Mull,
- Mary Granados,
- Mushira Kissebah,
- Kerri Russo,
- Robbin Crane,
- Michael Popp,
- Marc Peden,
- Tara Matise,
- Donna M. Brown,
- Jian Lu,
- Stephen Kingsmore,
- Peter J. Tonellato,
- Steve Rozen,
- Donna Slonim,
- Peter Young,
- Margit Knoblauch,
- Abraham Provoost,
- Detlev Ganten,
- Steven D. Colman,
- Jonathan Rothberg,
- Eric S. Lander,
- and Howard J. Jacob
Genome Res. June 1, 1999 9: AP1-AP8; Published in Advance May 21, 1999, doi:10.1101/gr.9.6.AP1
...Steven D. Simon, Twigger Anne Kwitek-Black Muir Melanie Matise, T T Mull R.G. Steen 1549-5469 genome;uu19991046R 10.1101/gr.9.6.AP1 1088-9051 A High-Density Integrated Genetic Linkage and Radiation Hybrid Map of the Laboratory Rat A High-Density Integrated Genetic Linkage and Radiation Hybrid Map...
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RESOURCE: Integration of the Rat Recombination and EST Maps in the Rat Genomic Sequence and Comparative Mapping Analysis With the Mouse Genome
- Steven P. Wilder,
- Marie-Thérèse Bihoreau,
- Karène Argoud,
- Takeshi K. Watanabe,
- Mark Lathrop,
- and Dominique Gauguier
Genome Res. April 2004 14: 758-765; doi:10.1101/gr.2001604
....S., Appel, D., Twigger, S., Muir, M., Mull, T., et al. 1999 . A high-density integrated genetic linkage and radiation hybrid map of the laboratory rat. Genome Res. 9 : 1 -8. ↵ Stoll, M., Kwitek-Black, A.E., Cowley Jr., A.W., Harris, E.L., Harrap, S.B., Krieger, J.E., Printz, M.P., Provoost, A.P., Sassard, J...
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Commentary: Every genome sequence needs a good map
- Harris A. Lewin,
- Denis M. Larkin,
- Joan Pontius,
- and Stephen J. O'Brien
Genome Res. November 2009 19: 1925-1928; Published in Advance July 13, 2009, doi:10.1101/gr.094557.109
..., Gullings-Handley J, Yu J, Carlos DC, Orlebeke K, Nie J, Eckert J, Lemke A, Andrae JW, Bromberg S, et al. 2004. High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat sequence. Genome Res 14: 750–757. Larkin DM, Everts-van der Wind A, Rebeiz M...
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Methods: Integrative Genomics: In Silico Coupling of Rat Physiology and Complex Traits With Mouse and Human Data
- Simon N. Twigger,
- Jeff Nie,
- Victor Ruotti,
- Jiaming Yu,
- Dan Chen,
- Dawei Li,
- Jed Mathis,
- Vijay Narayanasamy,
- Gopal R. Gopinath,
- Dean Pasko,
- Mary Shimoyama,
- Norberto de la Cruz,
- Susan Bromberg,
- Anne E. Kwitek,
- Howard J. Jacob,
- and Peter J. Tonellato
Genome Res. April 2004 14: 651-660; doi:10.1101/gr.1974504
....C., Orlebeke, K., Nie, J., Eckert, J., Lemke, A., Andrae, J.W., Bloomberg, S., et al. 2004 . High-density rat radiation hybrid maps containing over 24,000 SSLPs, genes, and ESTs provide a direct link to the rat sequence. Genome Res. (this issue). ↵ Laes, J.F., Ravoet, M., Quan, X., Van Vooren, P., Szpirer, J...
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LETTER: Lymphopenia in the BB Rat Model of Type 1 Diabetes is Due to a Mutation in a Novel Immune-Associated Nucleotide (Ian)-Related Gene
- Armand J. MacMurray,
- Daniel H. Moralejo,
- Anne E. Kwitek,
- Elizabeth A. Rutledge,
- Brian Van Yserloo,
- Paul Gohlke,
- Sara J. Speros,
- Ben Snyder,
- Jonathan Schaefer,
- Sabine Bieg,
- Jianjie Jiang,
- Ruth A. Ettinger,
- Jessica Fuller,
- Terri L. Daniels,
- Anna Pettersson,
- Kimberly Orlebeke,
- Bruce Birren,
- Howard J. Jacob,
- Eric S. Lander,
- and Åke Lernmark
Genome Res. July 1, 2002 12: 1029-1039; doi:10.1101/gr.412702
..., we constructed a rat YAC contig spanning the rat Iddm1/lyp region by isolating those rat YAC clones that contained the rat gene fragments. STS content mapping and hybridization of gene fragments from one map to the other confirmed that the local gene order was the same in rat and mouse (these...
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RESOURCE: Computational and Experimental Analysis of Microsatellites in Rice (Oryza sativa L.): Frequency, Length Variation, Transposon Associations, and Genetic Marker Potential
- Svetlana Temnykh,
- Genevieve DeClerck,
- Angelika Lukashova,
- Leonard Lipovich,
- Samuel Cartinhour,
- and Susan McCouch
Genome Res. August 1, 2001 11: 1441-1452; doi:10.1101/gr.184001
...://www.rice-research.org ) allows high-throughput in silico identification of SSR loci in sequenced regions, often with known map position, providing an excellent starting point for marker development. Conversely, mapped SSR markers that have been associated with phenotypes of interest provide a direct link to sequenced regions...
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LETTER: A Sequence-Ready BAC Contig of the GABA_A Receptor Gene Cluster Gabrg1–Gabra2–Gabrb1 on Mouse Chromosome 5
- Andreas Lengeling,
- Tim Wiltshire,
- Chris Otmani,
- and Maja Bućan
Genome Res. August 1, 1999 9: 732-738; doi:10.1101/gr.9.8.732
...in the following steps: (1) initial hybridization screen; (2) STS content mapping; (3) chromosome walk using selected STSs generated from BAC ends; and (4) fine mapping by fingerprinting and Southern blot analysis. To initiate the construction of a BAC contig, we used Gabra2 and Gabrg1 rat cDNA probes and a mouse...

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