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LETTER: A High-Resolution Physical Map of Human Chromosome 21p Using Yeast Artificial Chromosomes
- Sheng-Yue Wang,
- Marc Cruts,
- Jurgen Del-Favero,
- Yi Zhang,
- Fadel Tissir,
- Marie-Claude Potier,
- David Patterson,
- Dean Nizetic,
- Assumpció Bosch,
- Haiming Chen,
- Lynda Bennett,
- Xavier Estivill,
- Anna Kessling,
- Stylianos E. Antonarakis,
- and Christine van Broeckhoven
Genome Res. November 1, 1999 9: 1059-1073; doi:10.1101/gr.9.11.1059
...S. , Gerwehr S. , Cohen D. , Chumakov I. ( 1995 ) A high-fidelity physical map of human chromosome 21q in yeast artificial chromosomes. Genome Res. 5 : 427 – 443 . ↵ Korenberg J.R. , Aaltonen J. , Brahe C. , Cabin N. , Creau N. , Delabar J.M. , Doering J. , Gardiner K. , Hubert R.S. , Ives J. , et...
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ARTICLE: A new approach using multiplex long accurate PCR and yeast artificial chromosomes for bacterial chromosome mapping and sequencing.
- A Sorokin,
- A Lapidus,
- V Capuano,
- N Galleron,
- P Pujic,
- and S D Ehrlich
Genome Res. May 1996 6: 448-453; doi:10.1101/gr.6.5.448
....D. and Serror. P. 1993 . An ordered collection of Bacillus subtilis DNA segments cloned in yeast artificial chromosomes. Proc. Natl. Acad. Sci. 90 : 6047 – 6051 . Barnes, W.M. Barnes, W.M. 1994 . PCR amplification of up to 35-kb DNA with high fidelity and high yield from λ bacteriophage templates. Proc. Natl...
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LETTER: Physical and Comparative Mapping of Distal Mouse Chromosome 16
- Deborah E. Cabin,
- Jennifer W. McKee-Johnson,
- Lydia E. Matesic,
- Tim Wiltshire,
- Elizabeth E. Rue,
- Anne E. Mjaatvedt,
- Yong Kang Huo,
- Julie R. Korenberg,
- and Roger H. Reeves
Genome Res. September 1, 1998 8: 940-950; doi:10.1101/gr.8.9.940
.... , Cohen D. , Chumakov I. ( 1995 ) A high-fidelity physical map of human Chromosome 21q in yeast artificial chromosomes. Genome Res. 5 : 427 – 443 . ↵ Korenberg J.R. , Aaltonen J. , Brahe C. , Cabin D. , Creau N. , Delabar J.M. , Doering J. , Gardiner K. , Hubert R.S. , Ives J. , et al. ( 1997 ) Report...
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Research: Fusion, fission, and scrambling of the bilaterian genome in Bryozoa
- Thomas D. Lewin,
- Isabel Jiah-Yih Liao,
- Mu-En Chen,
- John D.D. Bishop,
- Peter W.H. Holland,
- and Yi-Jyun Luo
Genome Res. January 2025 35: 78-92; Published in Advance January 6, 2025, doi:10.1101/gr.279636.124
...Kingdom; 3Department of Biology, University of Oxford, Oxford OX1 3SZ, United Kingdom Corresponding author: yjluo@gate.sinica.edu.twAbstractGroups of orthologous genes are commonly found together on the same chromosome over vast evolutionary distances. This extensive physical gene linkage, known...
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RESEARCH: High-Resolution Physical and Transcriptional Mapping of the Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy Locus on Chromosome 21q22.3 by FISH
- Johanna Aaltonen,
- Nina Horelli-Kuitunen,
- Jian-Bing Fan,
- Petra Björses,
- Jaakko Perheentupa,
- Richard Myers,
- Aarno Palotie,
- and Leena Peltonen
Genome Res. August 1, 1997 7: 820-829; doi:10.1101/gr.7.8.820
....-N. , Mitchell S. , Fannin S. , Gerwehr S. , Cohen D. , Chumakov I. ( 1995 ) A high-fidelity physical map of human chromosome 21q in yeast artificial chromosomes. Genome Res. 5 : 427 – 443 . ↵ Kwok P.-Y. , Deng Q. , Zakeri H. , Scott S.L. , Nickerson D.A. ( 1996 ) Increasing the information content of STS...
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Review: A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest
- Andrew D. Bates,
- Dawid Grzela,
- Maciej Studzian,
- Louise Brennan,
- Moli Williams,
- Conor Fawcett,
- Beth Hammond,
- Manreen Grewal,
- Marcin Ratajewski,
- Lukasz Pulaski,
- and Urszula L. McClurg
Genome Res. March 2026 36: 433-459; Published in Advance February 17, 2026, doi:10.1101/gr.281154.125
...to it is the trans-element. The biological relevance of these elements must be evaluated individually. Analyzed DNA can be a synthetic, naked DNA sequence of in vitro origin; an artificial chromosome introduced into a cell (exogenous DNA); or endogenous DNA within the cell's . Exogenous DNA loses characteristics...
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Methods: Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements
- Josée Dostie,
- Todd A. Richmond,
- Ramy A. Arnaout,
- Rebecca R. Selzer,
- William L. Lee,
- Tracey A. Honan,
- Eric D. Rubio,
- Anton Krumm,
- Justin Lamb,
- Chad Nusbaum,
- Roland D. Green,
- and Job Dekker
Genome Res. October 2006 16: 1299-1309; Published in Advance September 5, 2006, doi:10.1101/gr.5571506
...Chromosome Conformation Capture Carbon Copy (5C): A massively parallel solution for mapping interactions between genomic elements Josée Dostie 1 , Todd A. Richmond 2 , Ramy A. Arnaout 3 , 4 , 5 , Rebecca R. Selzer 2 , William L. Lee 3...
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LETTER: Bacterial Contig Map of the 21q11 Region Associated with Alzheimer’s Disease and Abnormal Myelopoiesis in Down Syndrome
- Jürgen Groet,
- Jane H. Ives,
- Andrew P. South,
- Pedro R. Baptista,
- Tania A. Jones,
- Marie-Laure Yaspo,
- Hans Lehrach,
- Marie-Claude Potier,
- Christine Van Broeckhoven,
- and Dean Nižetić
Genome Res. April 1, 1998 8: 385-398; doi:10.1101/gr.8.4.385
...) with the physical and overlap map in Figure 1 , shows several distinct regions of homology. The first 200 kb of the contig seems to be the region shared by all acrocentric chromosomes, the next 220 kb is occupied by the duplicated region ( van Camp et al. 1992 ; Dutriaux et al. 1994 ; Potier et al. 1996 ), which...
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Research: Identification of dosage-sensitive genes in Saccharomyces cerevisiae using the genetic tug-of-war method
- Koji Makanae,
- Reiko Kintaka,
- Takashi Makino,
- Hiroaki Kitano,
- and Hisao Moriya
Genome Res. February 2013 23: 300-311; Published in Advance December 28, 2012, doi:10.1101/gr.146662.112
...the Methods). We amplified all proteincoding genes (5806) with their native regulatory regions in the yeast strain BY4741 chromosome using polymerase chain reaction (PCR) and then cloned the genes into pTOWug2-836 (Supplemental Fig. S1; Moriya et al. 2012). Because not all promoter regions were identified, we...
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ARTICLE: Human repeat-mediated integration of selectable markers into somatic cell hybrids.
- J E Watson,
- E M Slorach,
- J Maule,
- D Lawson,
- D J Porteous,
- and A J Brookes
Genome Res. December 1995 5: 444-452; doi:10.1101/gr.5.5.444
...encoded by a group I intron. Nucleic Acids Res. 18 : 1407 – 1412 . Pavan, W.J. , Reeves. R.H. Pavan, W.J. and Reeves. R.H. 1991 . Integrative selection of human chromosome-specific yeast artificial chromosomes. Proc. Natl. Acad. Sci. 88 : 7788 – 7791 . Porteous, D.J. Porteous, D.J. 1987 . Chromosome...

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