Searching journal content for articles similar to Koike et al. 13 (6a): 1231.

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  1. .../MAP2K, and STE20/PAK family members. We identified MARK1 in all screens and validated that DDX proteins accelerate the MARK1 catalytic rate. These findings indicate pervasive interactions between protein kinases and DEAD box RNA helicases, and provide a rich resource to explore their regulatory...
  2. ...annotation databases offer limited functional insights for sSNVs. Here, we present SynMall, a comprehensive resource designed to decipher the functional impact of synonymous variation. SynMall catalogs 25 million potential human sSNVs and integrates evolutionary and population information of sSNVs from 45...
  3. ...MPRAbase A Massively Parallel Reporter Assay database Jingjing Zhao1,2,*, Fotis A. Baltoumas3,*, Maxwell A. Konnaris4,5, Ioannis Mouratidis4, Zhe Liu1,2,6, Jasmine Sims1,2, Vikram Agarwal7, Georgios A. Pavlopoulos3, Ilias Georgakopoulos-Soares4,♱, Nadav Ahituv1,2,♱ 1Department of Bioengineering...
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  4. ...at a subset of RNAPII transcription termination regions marked by RNAPIII-transcribed tRNA and snRNA genes. Proteomic analyses identify distinct protein interaction networks comprising known chromatin regulators and novel trypanosome-specific components. Notably, several SET- and Bromo-domain protein networks...
  5. ...DNA molecules with an ∼1000-fold improvement in speed. In addition, we demonstrate that fibertools can readily integrate genetic and epigenetic data at single-molecule resolution, including the seamless conversion between molecular and reference coordinate systems, allowing for accurate genetic...
  6. ...-read SV calls were collected from http://ftp.1000s.ebi.ac.uk/vol1/ftp/data_collections/HGSVC2/release/v1.0/integrated_callset/.gnomADWe compared the HGDP + 1kGP resource to gnomAD v3.1.2, which includes both HGDP and 1kGP high-coverage whole s, to quantify the extent of novel variation across the allele...
  7. ...Complete s of Asgard archaea reveal diverse integrated and mobile genetic elements Luis E. Valentin-Alvarado1,2, Ling-Dong Shi1, Kathryn E. Appler3, Alexander Crits-Christoph1,2,11, Valerie De Anda3,4, Benjamin A. Adler1, Michael L. Cui1, Lynn Ly5, Pedro Leão3,12, Richard J. Roberts6, Rohan...
  8. ...integrated analysis at the transcriptome and epi levels to provide mechanistic insight (MoTrPAC Study Group et al. 2024; Nair et al. 2024). A limitation of this type of resource is that bulk tissue transcriptome and chromatin accessibility assays provide only an assessment of the average response across...
  9. ...://sysomics.com/AgingMap/), a manually curated online database of human and mouse aging-related genes. Aging Map first integrated six existing databases focused on different aspects of aging, including “Gene Ontology (GO)” (The Gene Ontology Consortium et al. 2000), “CSGene” (Zhao et al. 2016), “Aging Atlas” (Aging Atlas Consortium...
  10. ...are specifically recruited into mid-fetal brain, which contribute to the aforementioned brain bias of new genes.DiscussionWe developed GenTree as an integrated resource to facilitate the functional studies of new protein-coding genes in the human . The rich data underlying this database not only enable the -wide...
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