Searching journal content for articles similar to Kirsch et al. 15 (2): 195.

Displaying results 1-10 of 78

For checked items

view abstracts
download to citation manager

Select this article
Research: AGAP duplicons associate with structural diversity at Chromosome 10q11.22
- Stefania Fornezza,
- Vincenza Simona Delvecchio,
- William T. Harvey,
- Philip C. Dishuck,
- Evan E. Eichler,
- and Giuliana Giannuzzi
Genome Res. October 2024 34: 1487-1499; Published in Advance September 25, 2024, doi:10.1101/gr.279454.124
...of large, recent, and interspersed segmental duplications (SDs) (Marques-Bonet et al. 2009). These duplications are not evenly distributed along chromosomes but are clustered at some loci, especially pericentromeric and subtelomeric regions (Bailey et al. 2001; Giannuzzi et al. 2014). SD clusters exhibit...
Select this article
Method: HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads
- Sergey Nurk,
- Brian P. Walenz,
- Arang Rhie,
- Mitchell R. Vollger,
- Glennis A. Logsdon,
- Robert Grothe,
- Karen H. Miga,
- Evan E. Eichler,
- Adam M. Phillippy,
- and Sergey Koren
Genome Res. September 2020 30: 1291-1305; Published in Advance August 14, 2020, doi:10.1101/gr.263566.120
...correction, and aggressive false overlap filtering. We benchmark HiCanu with a focus on the recovery of haplotype diversity, major histocompatibility complex (MHC) variants, satellite DNAs, and segmental duplications. For diploid human s sequenced to 30× HiFi coverage, HiCanu achieved superior accuracy...
OPEN ACCESS ARTICLE
Select this article
Research: Hominoid fission of chromosome 14/15 and the role of segmental duplications
- Giuliana Giannuzzi,
- Michele Pazienza,
- John Huddleston,
- Francesca Antonacci,
- Maika Malig,
- Laura Vives,
- Evan E. Eichler,
- and Mario Ventura
Genome Res. November 2013 23: 1763-1773; Published in Advance September 27, 2013, doi:10.1101/gr.156240.113
...for three clones. For the homologous region on chromosome 14, we detected three human interchromosomal pericentromeric duplications (15q11, 18p11, and 21q11; Groups G2 and G3) dated to have duplicated prior to human–orangutan divergence (Supplemental Note). Furthermore, we identified a hominoid...
Select this article
Research: Interchromosomal core duplicons drive both evolutionary instability and disease susceptibility of the Chromosome 8p23.1 region
- Kiana Mohajeri,
- Stuart Cantsilieris,
- John Huddleston,
- Bradley J. Nelson,
- Bradley P. Coe,
- Catarina D. Campbell,
- Carl Baker,
- Lana Harshman,
- Katherine M. Munson,
- Zev N. Kronenberg,
- Milinn Kremitzki,
- Archana Raja,
- Claudia Rita Catacchio,
- Tina A. Graves,
- Richard K. Wilson,
- Mario Ventura,
- and Evan E. Eichler
Genome Res. November 2016 26: 1453-1467; Published in Advance October 7, 2016, doi:10.1101/gr.211284.116
...to the same interchromosomal core involved in the evolutionary formation of the duplication blocks. Our results define a higher-order genomic instability element that has shaped the structure of specific chromosomes during primate evolution contributing to rearrangements associated with inversion and disease...
Select this article
Research: Large tandem duplications affect gene expression, 3D organization, and plant–pathogen response
- Ariadna Picart-Picolo,
- Stefan Grob,
- Nathalie Picault,
- Michal Franek,
- Christel Llauro,
- Thierry Halter,
- Tom R. Maier,
- Edouard Jobet,
- Julie Descombin,
- Panpan Zhang,
- Vijayapalani Paramasivan,
- Thomas J. Baum,
- Lionel Navarro,
- Martina Dvořáčková,
- Marie Mirouze,
- and Frédéric Pontvianne
Genome Res. November 2020 30: 1583-1592; Published in Advance October 8, 2020, doi:10.1101/gr.261586.120
...on the short arm of Chromosome 4 (hk4s), a large heterochromatic region outside the pericentromeres, and a euchromatic region distal to the knob. Other TDDOs range in size from 60 to 370 kb long and are present on Chromosomes 1, 2, 4, and 5 (Fig. 1B). The absence/presence of TDDO4, the largest duplication...
OPEN ACCESS ARTICLE
Select this article
LETTER: Pericentromeric Duplications in the Laboratory Mouse
- James W. Thomas,
- Mary G. Schueler,
- Tyrone J. Summers,
- Robert W. Blakesley,
- Jennifer C. McDowell,
- Pamela J. Thomas,
- Jacquelyn R. Idol,
- Valerie V.B. Maduro,
- Shih-Queen Lee-Lin,
- Jeffrey W. Touchman,
- Gerard G. Bouffard,
- Stephen M. Beckstrom-Sternberg,
- NISC Comparative Sequencing Program,
- and Eric D. Green
Genome Res. January 1, 2003 13: 55-63; Published in Advance December 30, 2002, doi:10.1101/gr.791403
...the centromeres of the mouse chromosomes previously identified by cytogenetic mapping. We also identified pericentromeric duplicated segments shared between mouse chromosomes 5 and 1. Finally, novel mouse satellite sequences as well as putative chimeric transcripts were found to be associated with the duplicated...
Select this article
LETTER: A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications
- Xinwei She,
- Ge Liu,
- Mario Ventura,
- Shaying Zhao,
- Doriana Misceo,
- Roberta Roberto,
- Maria Francesca Cardone,
- Mariano Rocchi,
- NISC Comparative Sequencing Program,
- Eric D. Green,
- Nicoletta Archidiacano,
- and Evan E. Eichler
Genome Res. May 2006 16: 576-583; Published in Advance April 10, 2006, doi:10.1101/gr.4949406
...chromosomes (2.37%, 67.86 Mb). In addition, the sequence identity of intrachromosomal duplications is, on average, greater than that of interchromosomal duplications ( She et al. 2004b ). These properties have prompted speculation that the human and great-ape s have experienced a surge of intrachromosomal...
Select this article
LETTER: Evolutionary dynamics of segmental duplications from human Y-chromosomal euchromatin/heterochromatin transition regions
- Stefan Kirsch,
- Claudia Münch,
- Zhaoshi Jiang,
- Ze Cheng,
- Lin Chen,
- Christiane Batz,
- Evan E. Eichler,
- and Werner Schempp
Genome Res. July 2008 18: 1030-1042; Published in Advance April 29, 2008, doi:10.1101/gr.076711.108
...of segmental duplications originating from diverse euchromatic chromosomal regions are created by recurrent duplicative transpositions of diverse euchromatic segments into pericentromeric regions ( Jackson et al. 1999 ; Guy et al. 2000 , 2003 ; Horvath et al. 2000 , 2005 ; Locke et al. 2005 ). Differential...
Select this article
Resource: The genomic architecture of segmental duplications and associated copy number variants in dogs
- Thomas J. Nicholas,
- Ze Cheng,
- Mario Ventura,
- Katrina Mealey,
- Evan E. Eichler,
- and Joshua M. Akey
Genome Res. March 2009 19: 491-499; Published in Advance January 7, 2009, doi:10.1101/gr.084715.108
...(sd = 24.9 kb). We estimate that recent segmental duplications comprise ∼4.21% of the canine reference , which is consistent with similar observations in human and mouse ( Bailey et al. 2001 , 2002 , 2004 ; She et al. 2008 ). As expected, the “uncharacterized chromosome” (chrUn), which consists...
Select this article
ARTICLE: Analysis of Segmental Duplications and Genome Assembly in the Mouse
- Jeffrey A. Bailey,
- Deanna M. Church,
- Mario Ventura,
- Mariano Rocchi,
- and Evan E. Eichler
Genome Res. May 2004 14: 789-801; doi:10.1101/gr.2238404
...variation of the C57BL/6J strain. We conservatively estimate that ∼57% of all highly identical segmental duplications (≥90%) were misassembled or collapsed within the working draft WGS assembly. The WGS approach often leaves duplications fragmented and unassigned to a chromosome when compared with the clone...

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Kirsch et al. 15 (2): 195.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: