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REVIEW: Multiplex PCR: advantages, development, and applications.
- M C Edwards and
- R A Gibbs
Genome Res. February 1994 3: S65-S75
.... 20.. Klimpton, C.P., , Gill, P. , Walton, A. , Urquhart, A. , Millican, E.S. , Adams. M. Klimpton, C.P., Gill, P. Walton, A. Urquhart, A. Millican, E.S. and Adams. M. 1993 . Automated DNA profiling employing multiplex amplification of short tandem repeat loci. PCR Methods Applic. 3 13 – 21 . 21...
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ARTICLE: Sensitivity, reproducibility, and accuracy in short tandem repeat genotyping using capillary array electrophoresis.
- E S Mansfield,
- M Vainer,
- S Enad,
- D L Barker,
- D Harris,
- E Rappaport,
- and P Fortina
Genome Res. September 1996 6: 893-903; doi:10.1101/gr.6.9.893
.... , Gill. P. Kimpton, C.P., Disher, D. Watson, S. Adams, M. Urquhart, A. Lygo, J. and Gill. P. 1994 . Evaluation of an automated DNA profiling system employing multiplex amplification of four tetrameric STR loci. Int. J. Legal Med. 106 : 302 – 311 . Knowles, J.A., , Vieland, V.J. , Gilliam. T.C. Knowles, J...
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ARTICLES: Automated DNA profiling by fluorescent labeling of PCR products.
- K M Sullivan,
- S Pope,
- P Gill,
- and J M Robertson
Genome Res. August 1992 2: 34-40; doi:10.1101/gr.2.1.34
...Robertson Central Research and Support Establishment, Forensic Science Service, Reading, Berks, UK. Abstract DNA profiling has been automated by the fluorescent tagging of amplified variable number tandem repeat (VNTR) loci. This was achieved by the use of fluorescently labeled primers in the amplification...
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ARTICLE: A one-step coupled amplification and oligonucleotide ligation procedure for multiplex genetic typing.
- F A Eggerding
Genome Res. June 1995 4: 337-345
.... 1992 . Development, multiplexing, and application of ARMS tests for common mutations in the CFTR gene. Am. J. Hum. Genet. 51 : 251 – 262 . 11.. Fregeau, C.J. , Fourney. R.M. Fregeau, C.J. and Fourney. R.M. 1993 . DNA typing with fluorescently tagged short tandem repeats: A sensitive and accurate...
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Review: A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest
- Andrew D. Bates,
- Dawid Grzela,
- Maciej Studzian,
- Louise Brennan,
- Moli Williams,
- Conor Fawcett,
- Beth Hammond,
- Manreen Grewal,
- Marcin Ratajewski,
- Lukasz Pulaski,
- and Urszula L. McClurg
Genome Res. March 2026 36: 433-459; Published in Advance February 17, 2026, doi:10.1101/gr.281154.125
..., hinging on the precise binding of transcription factors (TFs) and cofactors to gene regulatory elements such as promoters and enhancers. Although it is relatively routine to profile -wide DNA binding landscapes of proteins, identifying the specific proteins that bind to, and regulate the transcription of...
OPEN ACCESS ARTICLE
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LETTER: High-Performance Multiplex SNP Analysis of Three Hemochromatosis-Related Mutations With Capillary Array Electrophoresis Microplates
- Igor Medintz,
- Wendy W. Wong,
- Lorenzo Berti,
- Lawrence Shiow,
- Jennifer Tom,
- James Scherer,
- George Sensabaugh,
- and Richard A. Mathies
Genome Res. March 1, 2001 11: 413-421; doi:10.1101/gr.164701
...into smaller monolithic platforms ( Kheterpal and Mathies 1999 ). High-speed sizing of DNA restriction fragments, PCR products, ASPCR products, and short tandem repeats as well as multiplex short tandem repeat (STR) typing have already been demonstrated on prototype microfabricated CE systems ( Woolley...
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ARTICLE: Approach to genotyping errors caused by nontemplated nucleotide addition by Taq DNA polymerase.
- J R Smith,
- J D Carpten,
- M J Brownstein,
- S Ghosh,
- V L Magnuson,
- D A Gilbert,
- J M Trent,
- and F S Collins
Genome Res. October 1995 5: 312-317; doi:10.1101/gr.5.3.312
..., A. Urquhart, A. Millican, E.S. and Adams. M. 1993 . Automated DNA profiling employing multiplex amplification of short tandem repeat loci. PCR Methods Applic. 3 : 13 – 22 . 6. Perlin, M.W., Burks, M.B. Hoop, R.C. and Hoffman. E.P. 1994 . Toward fully automated genotyping: Allele assignment, pedigree...
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Resource: Construction and evaluation of a new rat reference genome assembly, GRCr8, from long reads and long-range scaffolding
- Kai Li,
- Melissa L. Smith,
- J. Chris Blazier,
- Kelli J. Kochan,
- Jonathan M.D. Wood,
- Kerstin Howe,
- Anne E. Kwitek,
- Melinda R. Dwinell,
- Hao Chen,
- Julia L. Ciosek,
- Patrick Masterson,
- Terence D. Murphy,
- Theodore S. Kalbfleisch,
- and Peter A. Doris
Genome Res. November 2024 34: 2081-2093; Published in Advance November 8, 2024, doi:10.1101/gr.279292.124
.... The assembly has been adopted as the rat reference assembly by the Genome Reference Consortium and is named GRCr8. The assembly has employed 40× Pacific Biosciences (PacBio) HiFi sequencing coverage and scaffolding using optical mapping and Hi-C. We used genomic DNA from a male BN/NHsdMcwi (BN) rat of the same...
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Method: Paired-end sequencing of Fosmid libraries by Illumina
- Louise J.S. Williams,
- Diana G. Tabbaa,
- Na Li,
- Aaron M. Berlin,
- Terrance P. Shea,
- Iain MacCallum,
- Michael S. Lawrence,
- Yotam Drier,
- Gad Getz,
- Sarah K. Young,
- David B. Jaffe,
- Chad Nusbaum,
- and Andreas Gnirke
Genome Res. November 2012 22: 2241-2249; Published in Advance July 16, 2012, doi:10.1101/gr.138925.112
...(Margulies et al. 2005; McKernan et al. 2009) or with ‘‘colonies’’ of identical molecules grown by bridge PCR amplification on a solid surface (Bentley et al. 2008). However, none of these platforms can handle DNA molecules much longer than 1 kb. Consequently, paired-end sequencing of DNA fragments >1 kb...
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METHODS: High-Precision Genotyping by Denaturing Capillary Electrophoresis
- H.-Michael Wenz,
- James M. Robertson,
- Steve Menchen,
- Frank Oaks,
- David M. Demorest,
- Don Scheibler,
- Barnett B. Rosenblum,
- Carla Wike,
- Dennis A. Gilbert,
- and J. William Efcavitch
Genome Res. January 1, 1998 8: 69-80; doi:10.1101/gr.8.1.69
...and nucleic acids. Annu. Rev. Biophys. Biomol. Struct. 24 : 579 – 610 . ↵ Kimpton C.P. , Gill P. , Walton A. , Urquhart A. , Millican E.S. , Adams M. ( 1993 ) Automated DNA profiling employing multiplex amplification of short tandem repeat loci. PCR Methods Applic. 3 : 13 – 22 . ↵ Konrad K.D , Pentoney S...

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