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Method: Global mapping of RNA homodimers in living cells
- Marta M. Gabryelska,
- Andrew P. Badrock,
- Jian You Lau,
- Raymond T. O'Keefe,
- Yanick J. Crow,
- and Grzegorz Kudla
Genome Res. May 2022 32: 956-967; Published in Advance March 24, 2022, doi:10.1101/gr.275900.121
.... 2016), AGO1 CLASH HEK293 (Helwak et al. 2013), RNase E CLASH (Escherichia coli) (Waters et al. 2016), RIC-Seq HeLa (human) (Cai et al. 2020), and RPL (Saccharomyces cerevisiae) (Ramani et al. 2015; Methods).An intriguing pattern is the peak at overlap = 0 in Figure 2, indicating the preferential...
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LETTER: A Protein Interaction Framework for Human mRNA Degradation
- Ben Lehner and
- Christopher M. Sanderson
Genome Res. July 2004 14: 1315-1323; doi:10.1101/gr.2122004
...throughout the cell cycle or in response to cell signaling, suggesting that mRNA degradation is a regulated process ( Wilusz et al. 2001 ). To understand the control of gene expression, it is thus necessary to understand the regulation and mechanisms of mRNA degradation. In Saccharomyces cerevisiae , m...

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