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Research: Genome-wide and parental allele-specific analysis of CTCF and cohesin DNA binding in mouse brain reveals a tissue-specific binding pattern and an association with imprinted differentially methylated regions
- Adam R. Prickett,
- Nikolaos Barkas,
- Ruth B. McCole,
- Siobhan Hughes,
- Samuele M. Amante,
- Reiner Schulz,
- and Rebecca J. Oakey
Genome Res. October 2013 23: 1624-1635; Published in Advance June 26, 2013, doi:10.1101/gr.150136.112
...wide and in an allele-specific manner with high read-depth ChIP-seq. By comparing our results with existing data for mouse liver and embryonic stem (ES) cells, we investigated the tissue specificity of CTCF binding sites. ES cells have fewer unique CTCF binding sites occupied than liver and brain...
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Research: Human postmeiotic sex chromatin and its impact on sex chromosome evolution
- Ho-Su Sin,
- Yosuke Ichijima,
- Eitetsu Koh,
- Mikio Namiki,
- and Satoshi H. Namekawa
Genome Res. May 2012 22: 827-836; Published in Advance February 28, 2012, doi:10.1101/gr.135046.111
...silencing is likely to have impacted speciation, because genes specifically expressed in gametes may impinge on the success of fertilization and early embryonic development of the next generation. Therefore, we hypothesized if the acquisition of escape genes from postmeiotic silencing is beneficial...

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