Searching journal content for articles similar to Khrameeva et al. 30 (5): 776.

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  1. ...:Simulation-based evaluation of spatial reconstruction accuracyTo benchmark Polyomino against deconvolution-based spatial mapping methods, we constructed a simulation framework based on the STARMAP data set, which provides single-cell-resolution spatial transcriptomic data from the mouse brain. Spatial locations and gene...
  2. ...isoform reads and Illumina short reads available for three HGSOC patient samples sequenced at single-cell resolution. Here, tumor samples were derived from omental metastases, and for patient-1 and patient-3, matched normal omentum samples were available and similarly processed and analyzed for comparison...
  3. ..., which is characterized by several waves of gene upregulation and downregulation. We identified and in vivo validated cell-type-specific and position-specific regeneration-responsive enhancers and constructed regulatory networks by cell type and stage. Our single-cell resolution transcriptomic...
  4. ..., bacteria and yeast (Oelen et al. 2022), and influenza A (Randolph et al. 2021). Although different immune stimuli have been studied at single-cell resolution, the response to glucocorticoids has not been previously examined.Here, we used scRNA-seq to study the dynamics of the transcriptional response...
  5. ...Omnibus (GEO; https://www.ncbi.nlm.nih.gov/geo/) under accession number GSE152495. R code that was used to perform Seurat-based analyses with TopKLists is included in Supplemental Code and is available at GitHub (https://github.com/vshanka23/The-Drosophila-Brain-on-Cocaine-at-Single-Cell-Resolution...
  6. .... Corresponding authors: adey@ohsu.edu, sinnamon@ohsu.eduAbstractHere we present a comprehensive map of the accessible chromatin landscape of the mouse hippocampus at single-cell resolution. Substantial advances of this work include the optimization of a single-cell combinatorial indexing assay for transposase...
  7. ..., catalyzed by the adenosine deaminase acting on RNA (ADAR) enzymes, is a posttranscriptional process that modifies RNA sequences and diversifies the transcriptome. ADARs bind to double-stranded RNA (dsRNA) and their specificity and efficiency are affected by the structural properties of these substructures...
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  8. ...by their significant overlap (∼48%) with expression quantitative trait loci (eQTL) (Wang et al. 2018; Walker et al. 2019) and transcriptome-wide association study findings from fetal human brain (Gandal et al. 2018; Walker et al. 2019). Of the resulting panel of ∼72,000 targets, 65,000 were new as compared to Panel 1...
  9. ...retrotransposon subfamily activation in the early embryo, followed by repression in adult tissues. These data highlight endogenous macaque L1 retrotransposition potential, provide prototypical evidence of L1-mediated somatic mosaicism in a nonhuman primate, and allude to L1 mobility in the brain over the past 30...
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