Searching journal content for articles similar to Khambata et al. 6 (3): 195.

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  1. Research: Unraveling the architecture of major histocompatibility complex class II haplotypes in rhesus macaques
    • Nanine de Groot,
    • Marit van der Wiel,
    • Ngoc Giang Le,
    • Natasja G. de Groot,
    • Jesse Bruijnesteijn,
    • and Ronald E. Bontrop
    Genome Res. November 2024 34: 1811-1824; Published in Advance October 23, 2024, doi:10.1101/gr.278968.124
    ...) in concert with adaptive sampling. In particular, the expansion and contraction of the primate DRB-region appear to be a dynamic process that involves the rearrangement of different cassettes of paralogous genes. These chromosomal recombination events are propagated by a conserved pseudogene, DRB6, which...
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  2. LETTER: Haplotype Structure, LD Blocks, and Uneven Recombination Within the LRP5 Gene
    • Rebecca C.J. Twells,
    • Charles A. Mein,
    • Michael S. Phillips,
    • J. Fred Hess,
    • Riitta Veijola,
    • Matthew Gilbey,
    • Matthew Bright,
    • Michael Metzker,
    • Benedicte A. Lie,
    • Amanda Kingsnorth,
    • Edward Gregory,
    • Yusuke Nakagawa,
    • Hywel Snook,
    • William Y.S. Wang,
    • Jennifer Masters,
    • Gillian Johnson,
    • Iain Eaves,
    • Joanna M.M. Howson,
    • David Clayton,
    • Heather J. Cordell,
    • Sarah Nutland,
    • Helen Rance,
    • Philippa Carr,
    • and John A. Todd
    Genome Res. May 1, 2003 13: 845-855; doi:10.1101/gr.563703
    ...three genes, spanning 269 kb, for single nucleotide polymorphisms (SNPs), and we present a comprehensive SNP map comprising 95 polymorphisms. Analysis revealed high levels of recombination across LRP5 , including a hot-spot region from intron 1 to intron 7 of LRP5 , where there are 109 recombinants...
  3. LETTER: Haplotype and Linkage Disequilibrium Architecture for Human Cancer-Associated Genes
    • Penelope E. Bonnen,
    • Peggy J. Wang,
    • Marek Kimmel,
    • Ranajit Chakraborty,
    • and David L. Nelson
    Genome Res. December 1, 2002 12: 1846-1853; Published in Advance November 12, 2002, doi:10.1101/gr.483802
    ..., considerably more than the expected 1–2 kb for a recombination hot spot. A similar finding of an expansive region of little LD in two separate regions of Xq25 (129 kb and 308 kb) adds to the evidence that -wide LD patterns remain a complex issue that may only be resolved when a -wide map of LD is available...
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