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  1. .... 2015; Tokheim et al. 2016; Martincorena et al. 2017; Bailey et al. 2018).ResultsCI of the fitness effects detects selection on a variant setAs detailed in the Supplemental Information, our evolutionary calculus model hypothesizes a formal genotype–phenotype relationship. Differentiating...
  2. ...and wide association studies Supplemental material is available for this article For complex traits a mismatch between genotype and environment can cause a higher disease risk However it is generally difficult to determine the relevant environmental factors to measure in order to study gene...
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