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  1. ...and Guigó 2008). In this respect, there is growing evidence for abundant stop codon readthrough in insects, with UGA being the most frequently observed readthrough codon in Drosophila (Jungreis et al. 2011). Here, we have found additional strong evidence in support of the translational recoding of SPS1-UGA...
  2. ...acting at both levels of regulation. Finally, we also uncover multiple instances of stop-codon readthrough that are conserved between species. Our analysis reveals the underappreciated complexity of post-transcriptional regulatory divergence and indicates that partitioning the search for the locus...
  3. ...the full sequence, which is necessary when considering individual exons.We previously showed the ability of PhyloCSF and its predecessor, CSF, to add CDS annotation to s within the Schizosaccharomyces (Lin et al. 2011) and Drosophila lineages (Lin et al. 2007; The modENCODE Consortium et al. 2010; Jungreis...
  4. ...transcripts are genuinely expressed in human cells. Using high throughput RNA sequencing, mass spectrometry experimental data, and functional annotation, we studied 7424 putative human chimeric RNAs. We confirmed the expression of 175 chimeric RNAs in 16 human tissues, with an abundance varying from 0...
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