Searching journal content for articles similar to Jiao et al. 33 (5): 779.

Displaying results 1-10 of 17
For checked items
  1. ..., so too have methods for target enrichment using these platforms. Targeted long-read sequencing methods are powerful tools for studying genomic regions not readily accessible via short-read approaches. Targeted long reads provide enrichment for ROIs while maintaining variant positions within fragments...
    OPEN ACCESS ARTICLE
  2. ...in particular genes (Grafodatskaya et al. 2013; Barbosa et al. 2018). Illumina's Infinium MethylationEPIC array, which targets nearly a million methylation sites, is the most widely used platform for this analysis. Microarray methylation data, e.g., The Cancer Genome Atlas (TCGA) Research Network...
    OPEN ACCESS ARTICLE
  3. ...damage-dependent ubiquitination by OTUB2 supports the DNA repair pathway choice. Mol Cell 53: 617–630. ↵Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR. 2016. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature 533: 420–424. ↵Maeder ML, Gersbach CA. 2016...
  4. .... Genome Res 19: 1279–1288. Kim E, Kim S, Kim DH, Choi BS, Choi IY, Kim JS. 2012. Precision engineering with programmable DNA-nicking enzymes.Genome Res 22: 1327–1333. LeeHJ, KimE, Kim JS. 2010. Targeted chromosomal deletions in human cells using zinc finger nucleases. Genome Res 20: 81–89. Lee HJ, Kweon J...
  5. ...to gene editing in eukaryotes, but have been less widely adopted in the context of functional genomics due to the complexity involved in engineering meganucleases targeted to new sequences. Editing sequences with programmable nucleases Gene targeting based on homologous recombination can introduce...
    OPEN ACCESS ARTICLE
  6. ...-LTR with a characteristic ATCAG target site duplication (TSD). In scaffold_220592_3B, the TSDwas present on either side of the Sabrina_3231 element, while in the BAC-based scaffold Sabrina homology ended in Ns. In the BAC-based assembly, only one side of the disjunction showed alignment similarity to CACTA_3026, whichwas...
  7. ...difficulties encountered for certain genomic segments, such as duplications or highly repeated regions ( Bailey et al. 2004 ). Many of these imperfections are now being corrected, and the latest assembly released by the Mouse Genome Sequencing Consortium (NCBI build 34) has a length of 2.6 Gb, of which about 1...
  8. ...to investigate whether the human orthologs of a series of single-copy CD/CDY groups on the query chromosome are also found in a specific order and neighborhood on another chromosome (target). To compensate for genomic rearrangements, for example, chromosome inversions, translocations, tandem duplications...
  9. ..., Ferguson JM, Pineda SS, Scriba CK, Tchan M, Fung V, Ng K, Cortese A, et al. 2022. Comprehensive genetic diagnosis of tandem repeat expansion disorders with programmable targeted nanopore sequencing. Sci Adv 8: eabm5386. doi:10.1126/sciadv.abm5386 ↵Stranneheim H, Lagerstedt-Robinson K, Magnusson M, Kvarnung...
  10. ...Ullas V. Chembazhi1,5, Sushant Bangru1,2,5, Mikel Hernaez3,4 and Auinash Kalsotra1,2,3 1Department of Biochemistry, University of Illinois, Urbana, Illinois 61801, USA; 2Cancer Center@Illinois, University of Illinois, Urbana, Illinois 61801, USA; 3Carl R. Woese Institute for Genomic Biology...
For checked items

Preprint Server