Searching journal content for articles similar to Javasky et al. 28 (10): 1455.

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  1. ...experimentally showed the functional roles of such retained modifications at early stages: (i) H3K27ac premarks promoters during the cleavage stage, and inhibition of histone acetyltransferases disrupts proper patterning of H3K4 and H3K27 methylation at CpG-dense promoters, but does not affect chromatin...
  2. .... Yet, mitotic chromatin accessibility does not seem to correlate with mitotic binding, at least in the case of bookmarking by GATA1 in erythroblasts (Kadauke et al. 2012). Moreover, the maintenance of chromatin accessibility does not preclude the possibility that nucleosome positioning in mitotic cells...
  3. ...of start sites during mitosis. Third, loss of site-specific CTCF binding was directly demonstrated using CUT&RUN. Histone modifications and histone variants are maintained in mitosis, suggesting a role in bookmarking of active CTCF sites. Finally, live-cell imaging, fluorescence recovery after...
  4. ...the patterns of transcription factor binding in vivo (Kaplan et al. 2011; Li et al. 2011). However, the mechanisms that create sites of accessibility are poorly understood. It has been proposed that a special class of transcription factors, termed pioneer factors, binds nucleosomal DNA and increases chromatin...
  5. ...of actively transcribing genes by EHMT2. Taken together, these observations reveal that H3S10ph may play a general role in restricting the spreading of repressive chromatin in interphase mammalian cells.H3S10ph is a highly conserved histone post-translational modification (PTM); however, the influence...
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