Searching journal content for articles similar to Jagannathan and Bradley 26 (12): 1639.

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  1. ...and the developing nuclei (Lepère et al. 2009), and iesRNAs that relay a secondary excision signal to the developing nuclei (Sandoval et al. 2014). Besides facilitating IES excision, these sexually restricted small RNAs allow at least part of the genetic variability in the parental somatic nucleus to be inherited...
  2. ...is strongest when including all epochs (Supplemental Fig. S8). Further, the direction of effect is consistent across most epochs, with the exception of later epochs for which a smaller number of mutations have accumulated (Fig. 2C). Thus, we concluded the causal variant is segregating across the entire BXD...
  3. ...selection is FST (Weir 1996). Several variants of the classic FST statistic have been developed and applied to -wide scans of selection in humans, such as population-specific FST statistics (Shriver et al 2004; Weir et al. 2005), as well as more computationally sophisticated Bayesian methods of inference...
  4. ...splicing (AS) has been observed in genes associated with synaptic plasticity and neuronal function (Larsen et al. 2017; Patowary et al. 2024). As cells age, the accumulation of TN increases errors in gene expression and disrupts pathway coordination, making cells more susceptible to functional decline...
  5. ...(Shen et al. 2014). Specifically, CMT2 nonsense mutations in some populations are associated with temperature seasonality. We considered whether the extreme CMT2 STR alleles might be associated with these nonsense mutations. Instead, these extreme alleles exclusively occurred in strains with full...
  6. ..., there remains much to be understood about the splicing factors and the cis sequence elements controlling tissue and neuron subtype-specific splicing patterns. By using translating ribosome affinity purification coupled with deep-sequencing (TRAP-seq) in Caenorhabditis elegans, we have obtained high coverage...
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