Searching journal content for articles similar to Jacobsen et al. 20 (8): 1010.

Displaying results 1-10 of 79

For checked items

view abstracts
download to citation manager

Select this article
Research: Combinatorial microRNA activity is essential for the transition of pluripotent cells from proliferation into dormancy
- Dhanur P. Iyer,
- Lambert Moyon,
- Lars Wittler,
- Chieh-Yu Cheng,
- Francisca R. Ringeling,
- Stefan Canzar,
- Annalisa Marsico,
- and Aydan Bulut-Karslioğlu
Genome Res. April 2024 34: 572-589; Published in Advance May 6, 2024, doi:10.1101/gr.278662.123
...these processes are coordinated to successfully transition cells to the resting dormant state remains unclear. Here we show that microRNA activity, which is otherwise dispensable for preimplantation development, is essential for the adaptation of early mouse embryos to the dormant state of diapause. In particular...
Select this article
Resource: Genetic features and genomic targets of human KRAB-zinc finger proteins
- Jonas de Tribolet-Hardy,
- Christian W. Thorball,
- Romain Forey,
- Evarist Planet,
- Julien Duc,
- Alexandre Coudray,
- Bara Khubieh,
- Sandra Offner,
- Cyril Pulver,
- Jacques Fellay,
- Michael Imbeault,
- Priscilla Turelli,
- and Didier Trono
Genome Res. August 2023 33: 1409-1423; Published in Advance September 20, 2023, doi:10.1101/gr.277722.123
...et al. 2016; Durnaoglu et al. 2021). Accordingly, TEs are tamed by several general mechanisms, whether protein-based repressors such as the KZFP/TRIM28 or the HUSH complexes (Seczynska et al. 2022) or RNA-based mechanisms such as piRNAs (Ozata et al. 2019), the latter playing a prominent role...
OPEN ACCESS ARTICLE
Select this article
Research: Global analyses of the dynamics of mammalian microRNA metabolism
- Elena R. Kingston and
- David P. Bartel
Genome Res. November 2019 29: 1777-1790; Published in Advance September 13, 2019, doi:10.1101/gr.251421.119
...duplexes.Sequence differences and other features that mediate differences in guide half-livesTo address what might specify differences in guide half-lives, we assessed whether species with similar sequences had similar half-lives. MicroRNAs with the same seed region target largely overlapping sets of mRNAs...
Select this article
Research: Cooperative target mRNA destabilization and translation inhibition by miR-58 microRNA family in C. elegans
- Deni Subasic,
- Anneke Brümmer,
- Yibo Wu,
- Sérgio Morgado Pinto,
- Jochen Imig,
- Martin Keller,
- Marko Jovanovic,
- Helen Louise Lightfoot,
- Sara Nasso,
- Sandra Goetze,
- Erich Brunner,
- Jonathan Hall,
- Ruedi Aebersold,
- Mihaela Zavolan,
- and Michael O. Hengartner
Genome Res. November 2015 25: 1680-1691; Published in Advance July 31, 2015, doi:10.1101/gr.183160.114
...a framework for understanding how miRNA family members interact to regulate target mRNAs. [Supplemental material is available for this article.] MicroRNAs (miRNAs) are noncoding RNAmolecules of∼21 nucleotides in length that have an essential role in post-transcriptional regulation of gene expression...
Select this article
Method: Accurate transcriptome-wide identification and quantification of alternative polyadenylation from RNA-seq data with APAIQ
- Yongkang Long,
- Bin Zhang,
- Shuye Tian,
- Jia Jia Chan,
- Juexiao Zhou,
- Zhongxiao Li,
- Yisheng Li,
- Zheng An,
- Xingyu Liao,
- Yu Wang,
- Shiwei Sun,
- Ying Xu,
- Yvonne Tay,
- Wei Chen,
- and Xin Gao
Genome Res. April 2023 33: 644-657; Published in Advance April 28, 2023, doi:10.1101/gr.277177.122
...).Dysregulation of APA could be associated with human diseases, including cancer. It has been shown that APA-mediated 3′ UTR shortening could activate oncogene expression via escaping from microRNA regulation, whereas RNA transcripts with shortened 3′ UTRs could also inhibit other transcripts from tumor...
OPEN ACCESS ARTICLE
Select this article
Research: Tyrosine 1–phosphorylated RNA polymerase II transcribes PROMPTs to facilitate proximal promoter pausing and induce global transcriptional repression in response to DNA damage
- Kamal Ajit,
- Adele Alagia,
- Kaspar Burger,
- and Monika Gullerova
Genome Res. February 2024 34: 201-216; Published in Advance March 11, 2024, doi:10.1101/gr.278644.123
...of protein-coding genes (PCGs) and noncoding regulatory RNA species, such as microRNAs, small nuclear RNAs, and snoRNAs (Cramer et al. 2008). The RNA Pol II activity is a complex process that requires its interaction with multiple regulatory proteins. The largest subunit of RNA Pol II, RPB1, contains...
OPEN ACCESS ARTICLE
Select this article
Research: De novo transcriptome assembly of mouse male germ cells reveals novel genes, stage-specific bidirectional promoter activity, and noncoding RNA expression
- Mark E. Gill,
- Alexia Rohmer,
- Serap Erkek-Ozhan,
- Ching-Yeu Liang,
- Sunwoo Chun,
- Evgeniy A. Ozonov,
- and Antoine H.F.M. Peters
Genome Res. December 2023 33: 2060-2078; Published in Advance December 21, 2023, doi:10.1101/gr.278060.123
...meiosis, resulting in partial repression of the X and Y Chromosomes in spermatids (Namekawa et al. 2006). Some work has suggested that some X-linked transcripts (particularly microRNAs) can escape from MSCI (Song et al. 2009), although more recent work has argued against this (Royo et al. 2015).Following...
OPEN ACCESS ARTICLE
Select this article
Method: Genome-wide dynamics of RNA synthesis, processing, and degradation without RNA metabolic labeling
- Mattia Furlan,
- Eugenia Galeota,
- Nunzio Del Gaudio,
- Erik Dassi,
- Michele Caselle,
- Stefano de Pretis,
- and Mattia Pelizzola
Genome Res. October 2020 30: 1492-1507; Published in Advance September 25, 2020, doi:10.1101/gr.260984.120
...both total and nascent RNA (de Pretis et al. 2017). In that study, the integrative analysis of both data types with the INSPEcT+ approach revealed that MYC acts predominantly by modulating the rate of synthesis of its target genes, with an important, albeit less prevalent, impact on processing...
OPEN ACCESS ARTICLE
Select this article
Method: Identification of microRNA-regulated gene networks by expression analysis of target genes
- Vincenzo Alessandro Gennarino,
- Giovanni D'Angelo,
- Gopuraja Dharmalingam,
- Serena Fernandez,
- Giorgio Russolillo,
- Remo Sanges,
- Margherita Mutarelli,
- Vincenzo Belcastro,
- Andrea Ballabio,
- Pasquale Verde,
- Marco Sardiello,
- and Sandro Banfi
Genome Res. June 2012 22: 1163-1172; Published in Advance February 15, 2012, doi:10.1101/gr.130435.111
...-expression analysis as a general paradigm for second-generation procedures to recognize bona fide targets and infer biological roles and network communities of miRNAs. [Supplemental material is available for this article.] MicroRNAs (miRNAs) are small noncodingRNAs that have basic roles in the control of gene...
Select this article
Perspective: Decrypting noncoding RNA interactions, structures, and functional networks
- Muller Fabbri,
- Leonard Girnita,
- Gabriele Varani,
- and George A. Calin
Genome Res. September 2019 29: 1377-1388; Published in Advance August 21, 2019, doi:10.1101/gr.247239.118
.... 2017). Over the last decade, advances in bioinformatics and deep sequencing technology have allowed the identification and annotation of tens of thousands of short and long ncRNAs (lncRNAs). These include endogenous microRNAs (miRNAs), small interfering RNAs (endo-siRNAs), PIWI-interacting RNAs (piRNAs...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Jacobsen et al. 20 (8): 1010.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: