Searching journal content for articles similar to Imamachi et al. 27 (3): 407.

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  1. Research: Translation-dependent and -independent mRNA decay occur through mutually exclusive pathways defined by ribosome density during T cell activation
    • Blandine C. Mercier,
    • Emmanuel Labaronne,
    • David Cluet,
    • Laura Guiguettaz,
    • Nicolas Fontrodona,
    • Alicia Bicknell,
    • Antoine Corbin,
    • Mélanie Wencker,
    • Fabien Aube,
    • Laurent Modolo,
    • Karina Jouravleva,
    • Didier Auboeuf,
    • Melissa J. Moore,
    • and Emiliano P. Ricci
    Genome Res. March 2024 34: 394-409; Published in Advance March 20, 2024, doi:10.1101/gr.277863.123
    ...length and, to a lesser extent, to 5′ UTR length among important factors explaining TDD (Fig. 2A). Further analysis confirmed a global anticorrelation between UTR length and TDD susceptibility (Fig. 2B). This result was surprising because long 3′ UTRs had been linked to UPF1-dependent mRNA decay (Hogg...
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  2. Research: A massively parallel 3′ UTR reporter assay reveals relationships between nucleotide content, sequence conservation, and mRNA destabilization
    • Adam J. Litterman,
    • Robin Kageyama,
    • Olivier Le Tonqueze,
    • Wenxue Zhao,
    • John D. Gagnon,
    • Hani Goodarzi,
    • David J. Erle,
    • and K. Mark Ansel
    Genome Res. June 2019 29: 896-906; Published in Advance May 31, 2019, doi:10.1101/gr.242552.118
    ...directs mRNA decay through binding to CUG motifs within GC-rich regions of target 3′ UTRs (Imamachi et al. 2017). STAU1 binds promiscuously to tightly folded sequences in 3′ UTRs of transcripts throughout the , typified by runs of guanines base-paired with pyrimidine rich tracts. There may be other RBPs...
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