Searching journal content for articles similar to Ideraabdullah et al. 14 (10a): 1880.

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  1. ...-relevant traits have been characterized in mice and made publicly available. New strains and populations including consomics, the collaborative cross, expanded BXD, and inbred wild-derived strains add to existing complex disease mouse models, mapping populations, and sensitized backgrounds for engineered...
  2. ...activity (Tanaka et al. 1991). Yang et al. (2011) reported that the origins and compositions of the s of classical inbred strains depend on the use of wild-derived inbred strains as reference s to infer subspecific origin. This is because some wild-derived inbred strains suffered intersubspecific...
  3. ...this (Scavetta and Tautz 2010; Cocquet et al. 2012). Morgan and Pardo-Manuel (2017) showed that the subspecies musculus tended to have higher Sly/Slx copy numbers than other subspecies, but their analyzed samples were biased toward wild-derived inbred lines (Morgan and Pardo-Manuel de Villena 2017). Therefore...
  4. ...in independent C57BL/6J mouse samples (data not shown). The strains with the largest numbers of CNVs (SPRET/EiJ, CZECHII/EiJ, PWK/PhJ, MOLF/EiJ, JF1/Ms, CAST/EiJ), being wild-derived, are the most genetically distant from the reference C57BL/6J strain as one would expect. Likewise, the strains with the fewest...
  5. ...: Their APOA2 sequence had an Ala 61 -to-Val 61 substitution, and none of them were wild-derived strains (all were inbred laboratory mice). The other APOA2 types each had at least one wild-derived strain: “a” type contains M. m. castaneus, M. m. musculus , and M. m. molossinus (a mixture of the previous two...
  6. ...mouse strains is needed. Here, we use high-density oligonucleotide arrays to discover an extremely dense set of SNPs in 13 classical and two wild-derived inbred strains in five genomic intervals totaling 4.6 Mb of DNA sequence, and then analyze the segmental haplotype structure defined by these high...
  7. ..., a third haplotype was found in the wild-derived strains PERA/Pk, PERC/Ei, and ZALENDE/Ei but not in the laboratory inbred strains. Haplotypes of the last two SNPs polymorphic in domesticus strains (marked by red asterisks in Fig. 7A ) in segment 1 are biallelic (among the wild-derived domesticus strains...
  8. ...corresponding investigations in humans (Schughart et al. 2013). Insights from mouse models Initially, investigators relied on existing genetic and phenotypic diversity among the many inbred strains of mice. Thousands and perhaps millions of DNA sequence variants that differ among these strains contribute...
  9. ...involved contrasts between wild-derived founder strains and therefore would not segregate between classical inbred strains. Use of variation data from the genomes of the CC founder strains refined these QTLs further and suggested several candidate genes. These results support the use of the CC...
  10. ...strains, including five classical inbred strains (A/J, C57BL/6J, 129S1/SvImJ, NOD/LtJ, and NZO/H1LtJ) and three wild-derived strains representing the three Mus musculus subspecies (CAST/EiJ, PWK/PhJ, and WSB/EiJ). The eight founder strains capture a level of genetic diversity unsurpassed by any existing...
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