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Research: Aberrant PRDM9 expression impacts the pan-cancer genomic landscape
- Armande Ang Houle,
- Heather Gibling,
- Fabien C. Lamaze,
- Hilary A. Edgington,
- David Soave,
- Marie-Julie Fave,
- Mawusse Agbessi,
- Vanessa Bruat,
- Lincoln D. Stein,
- and Philip Awadalla
Genome Res. November 2018 28: 1611-1620; Published in Advance October 19, 2018, doi:10.1101/gr.231696.117
..., Casals F, Idaghdour Y, Bruat V, Saillour V, Healy J, Grenier J, de Malliard T, Busche S, et al. 2013. Rare allelic forms of PRDM9 associated with childhood leukemogenesis. Genome Res 23: 419–430. ↵Hussin JG, Hodgkinson A, Idaghdour Y, Grenier J-C, Goulet J-P, Gbeha E, Hip-Ki E, Awadalla P. 2015...
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Method: Identifying chromosomal subpopulations based on their recombination histories advances the study of the genetic basis of phenotypic traits
- Carlos Ruiz-Arenas,
- Alejandro Cáceres,
- Marcos López,
- Dolors Pelegrí-Sisó,
- Josefa González,
- and Juan R. González
Genome Res. December 2020 30: 1802-1814; Published in Advance November 17, 2020, doi:10.1101/gr.258301.119
...recombClust, a method that uses SNP-phased data to detect differences in historic recombination in a chromosome population. We validated our method by performing simulations and by using real data to accurately predict the alleles of well-known recombination modifiers, including common inversions...

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