Searching journal content for articles similar to Howell et al. 12 (9): 1401.

Displaying results 1-10 of 4483

For checked items

view abstracts
download to citation manager

Select this article
Methods: Accurate quantitation of allele-specific expression patterns by analysis of DNA melting
- Sangkyun Jeong,
- Yoonsoo Hahn,
- Qi Rong,
- and Karl Pfeifer
Genome Res. July 2007 17: 1093-1100; Published in Advance June 1, 2007, doi:10.1101/gr.6028507
...), or from a 1:1 volume mixture of 129 and FVB cDNAs (yellow triangles). DNA melting is assayed by loss of fluorescence at 640 nm and then normalized as described in the text so that the Y -axis reflects the relative fraction of remaining dsDNA [γ(dsDNA)]. Note the leftward shift of the 129 cDNA melting...
Select this article
Method: Improved discovery of genetic interactions using CRISPRiSeq across multiple environments
- Mia Jaffe,
- Adam Dziulko,
- Justin D. Smith,
- Robert P. St.Onge,
- Sasha F. Levy,
- and Gavin Sherlock
Genome Res. April 2019 29: 668-681; Published in Advance February 19, 2019, doi:10.1101/gr.246603.118
...in five conditions and found that the additional conditions increased the number of GIs detected nearly threefold over the number detected in rich media alone. In addition, we found that condition-specific GIs are prevalent and improved the power to functionally classify genes. Finally, we found new links...
OPEN ACCESS ARTICLE
Select this article
Method: Background-suppressed live visualization of genomic loci with an improved CRISPR system based on a split fluorophore
- Narendra Chaudhary,
- Si-Hyeong Nho,
- Hayoon Cho,
- Narangerel Gantumur,
- Jae Sun Ra,
- Kyungjae Myung,
- and Hajin Kim
Genome Res. September 2020 30: 1306-1316; Published in Advance September 4, 2020, doi:10.1101/gr.260018.119
...-positive signals (Hong et al. 2018; Wu et al. 2019). In another study, weak fluorescence signals and low S/B were improved by the use of mNeonGreen tetramer (Ye et al. 2017). Our design, incorporating tripartite sfGFP and the SunTag system, is unique in that it yielded lower signal levels but much higher S/B due...
Select this article
Research: Improved redox homeostasis owing to the up-regulation of one-carbon metabolism and related pathways is crucial for yeast heterosis at high temperature
- Liang Song,
- Jun-Yan Shi,
- Shou-Fu Duan,
- Da-Yong Han,
- Kuan Li,
- Ri-Peng Zhang,
- Peng-Yu He,
- Pei-Jie Han,
- Qi-Ming Wang,
- and Feng-Yan Bai
Genome Res. April 2021 31: 622-634; Published in Advance March 15, 2021, doi:10.1101/gr.262055.120
...associated with one-carbon metabolism and related pathways were generally up-regulated in the heterotic F1 hybrids, leading to improved cellular redox homeostasis at high temperature. Consistently, genes related with DNA repair, stress responses, and ion homeostasis were generally down...
Select this article
Method: Whole-genome bisulfite sequencing with improved accuracy and cost
- Masako Suzuki,
- Will Liao,
- Frank Wos,
- Andrew D. Johnston,
- Justin DeGrazia,
- Jennifer Ishii,
- Toby Bloom,
- Michael C. Zody,
- Soren Germer,
- and John M. Greally
Genome Res. September 2018 28: 1364-1371; Published in Advance August 9, 2018, doi:10.1101/gr.232587.117
...Whole- bisulfite sequencing with improved accuracy and cost Masako Suzuki1,3, Will Liao2,3, Frank Wos2,3, Andrew D. Johnston1, Justin DeGrazia2, Jennifer Ishii2, Toby Bloom2, Michael C. Zody2, Soren Germer2 and John M. Greally1 1Center for Epigenomics and Department of Genetics, Albert Einstein...
Select this article
Research: Sequence determinants of improved CRISPR sgRNA design
- Han Xu,
- Tengfei Xiao,
- Chen-Hao Chen,
- Wei Li,
- Clifford A. Meyer,
- Qiu Wu,
- Di Wu,
- Le Cong,
- Feng Zhang,
- Jun S. Liu,
- Myles Brown,
- and X. Shirley Liu
Genome Res. August 2015 25: 1147-1157; Published in Advance June 10, 2015, doi:10.1101/gr.191452.115
...different from that for CRISPR/Cas9 knockout and propose a new model for predicting sgRNA efficiency in CRISPRi/a experiments. These results facilitate the -wide design of improved sgRNA for both knockout and CRISPRi/a studies.The clustered regularly interspaced short palindromic repeats (CRISPR) system...
Select this article
Method: Improved assembly of noisy long reads by k-mer validation
- Antonio Bernardo Carvalho,
- Eduardo G. Dupim,
- and Gabriel Goldstein
Genome Res. December 2016 26: 1710-1720; Published in Advance October 7, 2016, doi:10.1101/gr.209247.116
...Improved assembly of noisy long reads by k -mer validation Antonio Bernardo Carvalho , Eduardo G. Dupim and Gabriel Goldstein Departamento de Genética, Universidade Federal do Rio de Janeiro, CEP 21941-971, Rio de Janeiro, Brazil...
Select this article
Resource: Improved definition of the mouse transcriptome via targeted RNA sequencing
- Giovanni Bussotti,
- Tommaso Leonardi,
- Michael B. Clark,
- Tim R. Mercer,
- Joanna Crawford,
- Lorenzo Malquori,
- Cedric Notredame,
- Marcel E. Dinger,
- John S. Mattick,
- and Anton J. Enright
Genome Res. May 2016 26: 705-716; doi:10.1101/gr.199760.115
...Improved definition of the mouse transcriptome via targeted RNA sequencing Giovanni Bussotti 1 , 7 , Tommaso Leonardi 1 , Michael B. Clark 2 , 3 , Tim R. Mercer 2 , 4 , Joanna Crawford 5 , Lorenzo Malquori 5 , Cedric...
OPEN ACCESS ARTICLE
Select this article
Research: Improved genome assembly of American alligator genome reveals conserved architecture of estrogen signaling
- Edward S. Rice,
- Satomi Kohno,
- John St. John,
- Son Pham,
- Jonathan Howard,
- Liana F. Lareau,
- Brendan L. O'Connell,
- Glenn Hickey,
- Joel Armstrong,
- Alden Deran,
- Ian Fiddes,
- Roy N. Platt II,
- Cathy Gresham,
- Fiona McCarthy,
- Colin Kern,
- David Haan,
- Tan Phan,
- Carl Schmidt,
- Jeremy R. Sanford,
- David A. Ray,
- Benedict Paten,
- Louis J. Guillette, Jr.,
- and Richard E. Green
Genome Res. May 2017 27: 686-696; Published in Advance January 30, 2017, doi:10.1101/gr.213595.116
...Improved assembly of American alligator reveals conserved architecture of estrogen signaling Edward S. Rice,1 Satomi Kohno,2 John St. John,3 Son Pham,4 Jonathan Howard,5 Liana F. Lareau,6 Brendan L. O’Connell,1,7 Glenn Hickey,1 Joel Armstrong,1 Alden Deran,1 Ian Fiddes,1 Roy N. Platt II,8 Cathy...
Select this article
Review: A systematic guide for identifying transcription factors that directly regulate the expression of a gene of interest
- Andrew D. Bates,
- Dawid Grzela,
- Maciej Studzian,
- Louise Brennan,
- Moli Williams,
- Conor Fawcett,
- Beth Hammond,
- Manreen Grewal,
- Marcin Ratajewski,
- Lukasz Pulaski,
- and Urszula L. McClurg
Genome Res. March 2026 36: 433-459; Published in Advance February 17, 2026, doi:10.1101/gr.281154.125
..., have significantly improved database quality (Jolma et al. 2013). However, the human has nearly 2000 transcription regulators, many of which share consensus sites, adding complexity to predictions (Lambert et al. 2018).Despite improvements, PWM-based predictions suffer from high false positives owing...
OPEN ACCESS ARTICLE

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Howell et al. 12 (9): 1401.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: