Searching journal content for articles similar to Howarth et al. 21 (4): 525.

Displaying results 1-10 of 5532

For checked items

view abstracts
download to citation manager

Select this article
Resource: An integrative TAD catalog in lymphoblastoid cell lines discloses the functional impact of deletions and insertions in human genomes
- Chong Li,
- Marc Jan Bonder,
- Sabriya Syed,
- Matthew Jensen,
- Human Genome Structural Variation Consortium (HGSVC),
- HGSVC Functional Analysis Working Group,
- Mark B. Gerstein,
- Michael C. Zody,
- Mark J.P. Chaisson,
- Michael E. Talkowski,
- Tobias Marschall,
- Jan O. Korbel,
- Evan E. Eichler,
- Charles Lee,
- and Xinghua Shi
Genome Res. December 2024 34: 2304-2318; Published in Advance December 5, 2024, doi:10.1101/gr.279419.124
...regulation resulting from pathogenic large genomic rearrangements or structural variants (SVs), including deletions, insertions, inversions, and duplications (Shanta et al. 2020). These genomic rearrangements can disturb the normal 3D structure of the and lead to aberrant interactions between chromatin...
Select this article
Method: Parallel analysis of replication timing, gene expression, and copy number with PARTAGE
- Lakshana Sruthi Sadu Murari,
- Quinn Dickinson,
- Silvia Meyer-Nava,
- and Juan Carlos Rivera-Mulia
Genome Res. March 19, 2026 ; Published in Advance March 19, 2026, doi:10.1101/gr.281532.125
...profiles derived from ENCODE high-coverage WGS (60× coverage; top track) and from PARTAGE (∼0.5× coverage; three independent replicates) using CNVpytor (see Methods). CNV segments identified in the ENCODE data set (n = 25 events) are shown as duplications (blue) and deletions (red) and were used...
OPEN ACCESS ARTICLE
Select this article
Research: Chromatin interaction maps identify oncogenic targets of enhancer duplications in cancer
- Yueqiang Song,
- Fuyuan Li,
- Shangzi Wang,
- Yuntong Wang,
- Cong Lai,
- Lian Chen,
- Ning Jiang,
- Jin Li,
- Xingdong Chen,
- Swneke D. Bailey,
- and Xiaoyang Zhang
Genome Res. October 2024 34: 1514-1527; Published in Advance October 18, 2024, doi:10.1101/gr.278418.123
...recurrently duplicated regions in the in an unbiased manner. The PCAWG project has identified 288,417 somatic structural variants, including duplications, deletions, inversions, and translocations, in 2439 samples across 37 cancer types (The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium 2020...
Select this article
Research: Cell-type- and chromosome-specific chromatin landscapes and DNA replication programs of Drosophila testis tumor stem cell–like cells
- Jennifer A. Urban,
- Daniel Ringwalt,
- John M. Urban,
- Wingel Xue,
- Ryan Gleason,
- Keji Zhao,
- and Xin Chen
Genome Res. January 2026 36: 83-101; Published in Advance December 10, 2025, doi:10.1101/gr.280809.125
...for these domains across different cell types.Cell-type-specific replication timing correlates with histone modification patternsThe temporal order of duplication in eukaryotic cells is intricately linked to chromatin structure and gene expression, both of which are cell-type specific (Rhind and Gilbert 2013...
OPEN ACCESS ARTICLE
Select this article
Research: Elevated variant density around SV breakpoints in germline lineage lends support to error-prone replication hypothesis
- Dhananjay Dhokarh and
- Alexej Abyzov
Genome Res. July 2016 26: 874-881; Published in Advance May 23, 2016, doi:10.1101/gr.205484.116
...et al. 2013; Pang et al. 2013; Abyzov et al. 2015; Wang et al. 2015). CGRs are characterized by the presence of two ormore breakpoint junctions and combinations ofmultiple simple rearrangements, such as deletions, duplications, inversions, and also triplications (Zhang et al. 2009a). Two replicative...
Select this article
Research: Delayed DNA replication in haploid human embryonic stem cells
- Matthew M. Edwards,
- Michael V. Zuccaro,
- Ido Sagi,
- Qiliang Ding,
- Dan Vershkov,
- Nissim Benvenisty,
- Dieter Egli,
- and Amnon Koren
Genome Res. December 2021 31: 2155-2169; Published in Advance November 22, 2021, doi:10.1101/gr.275953.121
...-Chromosome dosage may cause delayed autosomal replication. We propose that incomplete replication at the onset of mitosis could prevent cell division and result in re-entry into the cell cycle and whole duplication.Embryonic stem cells are typically derived from in vitro fertilization of human oocytes...
Select this article
Research: Large tandem duplications affect gene expression, 3D organization, and plant–pathogen response
- Ariadna Picart-Picolo,
- Stefan Grob,
- Nathalie Picault,
- Michal Franek,
- Christel Llauro,
- Thierry Halter,
- Tom R. Maier,
- Edouard Jobet,
- Julie Descombin,
- Panpan Zhang,
- Vijayapalani Paramasivan,
- Thomas J. Baum,
- Lionel Navarro,
- Martina Dvořáčková,
- Marie Mirouze,
- and Frédéric Pontvianne
Genome Res. November 2020 30: 1583-1592; Published in Advance October 8, 2020, doi:10.1101/gr.261586.120
...of several millions of years, numerous rearrangements have occurred to shape the Arabidopsis thaliana , including duplications, translocations, inversions, and deletions (Blanc et al. 2000; Henry et al. 2006). Recently, analysis of seven accessions of A. thaliana revealed that they contain, on average, 15 Mb...
OPEN ACCESS ARTICLE
Select this article
Research: Sense–antisense miRNA pairs constitute an elaborate reciprocal regulatory circuit
- Yulong Song,
- Lishi Li,
- Wenbing Yang,
- Qiang Fu,
- Wanying Chen,
- Zeng Fang,
- Wen Li,
- Nannan Gu,
- and Rui Zhang
Genome Res. May 2020 30: 661-672; Published in Advance May 18, 2020, doi:10.1101/gr.257121.119
...as a previously unknown reciprocal regulatory circuit of sense–antisense miRNA pairs.One of the greatest surprises of recent transcriptome analysis is the discovery that the mammalian is pervasively transcribed (Kapranov et al. 2002; Carninci et al. 2005) and many of the protein-coding genes have antisense...
Select this article
Research: Unbalanced translocations arise from diverse mutational mechanisms including chromothripsis
- Brooke Weckselblatt,
- Karen E. Hermetz,
- and M. Katharine Rudd
Genome Res. July 2015 25: 937-947; Published in Advance June 12, 2015, doi:10.1101/gr.191247.115
...-induced replication. Three simple translocations fuse genes that are predicted to produce in-frame transcripts of SIRPG-WWOX , SMOC2-PROX1 , and PIEZO2-MTA1 , which may lead to gain of function. Three complex translocations have inversions, insertions, and multiple breakpoint junctions between only two chromosomes...
Select this article
Research: Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy
- David W. Radke,
- Jae Hoon Sul,
- Daniel J. Balick,
- Sebastian Akle,
- Alzheimer's Disease Neuroimaging Initiative,
- Robert C. Green,
- and Shamil R. Sunyaev
Genome Res. June 2021 31: 935-946; Published in Advance May 7, 2021, doi:10.1101/gr.275263.121
...STRiP (Handsaker et al. 2011). We additionally used deletion data (Supplemental Note S2) from The 1000 Genomes Project Consortium (1000GP) phase 3 callset of breakpoint-resolved deletions that had been genotyped in 2504 individuals from 26 modern human populations (Sudmant et al. 2015a). We restricted...

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Howarth et al. 21 (4): 525.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: