Searching journal content for articles similar to Holden et al. 23 (4): 653.

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  1. Resource: Building a genomic framework for prospective MRSA surveillance in the United Kingdom and the Republic of Ireland
    • Sandra Reuter,
    • M. Estée Török,
    • Matthew T.G. Holden,
    • Rosy Reynolds,
    • Kathy E. Raven,
    • Beth Blane,
    • Tjibbe Donker,
    • Stephen D. Bentley,
    • David M. Aanensen,
    • Hajo Grundmann,
    • Edward J. Feil,
    • Brian G. Spratt,
    • Julian Parkhill,
    • and Sharon J. Peacock
    Genome Res. February 2016 26: 263-270; Published in Advance December 15, 2015, doi:10.1101/gr.196709.115
    ...Natl Acad Sci 101: 9786–9791. Holden MT, Hsu LY, Kurt K, Weinert LA, Mather AE, Harris SR, Strommenger B, Layer F,WitteW, de LencastreH, et al. 2013. A genomic portrait of the emergence, evolution, and global spread of a methicillinresistant Staphylococcus aureus pandemic. Genome Res 23: 653...
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  2. Research: Predicting the virulence of MRSA from its genome sequence
    • Maisem Laabei,
    • Mario Recker,
    • Justine K. Rudkin,
    • Mona Aldeljawi,
    • Zeynep Gulay,
    • Tim J. Sloan,
    • Paul Williams,
    • Jennifer L. Endres,
    • Kenneth W. Bayles,
    • Paul D. Fey,
    • Vijaya Kumar Yajjala,
    • Todd Widhelm,
    • Erica Hawkins,
    • Katie Lewis,
    • Sara Parfett,
    • Lucy Scowen,
    • Sharon J. Peacock,
    • Matthew Holden,
    • Daniel Wilson,
    • Timothy D. Read,
    • Jean van den Elsen,
    • Nicholas K. Priest,
    • Edward J. Feil,
    • Laurence D. Hurst,
    • Elisabet Josefsson,
    • and Ruth C. Massey
    Genome Res. May 2014 24: 839-849; Published in Advance April 9, 2014, doi:10.1101/gr.165415.113
    ...and adhesiveness of 90 MRSA (methicillin resistant S. aureus ) isolates and found that while there was remarkably little variation in adhesion, toxicity varied by over an order of magnitude between isolates, suggesting different evolutionary selection pressures acting on these two traits. We performed a genome...
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  3. Research: Genome specialization and decay of the strangles pathogen, Streptococcus equi, is driven by persistent infection
    • Simon R. Harris,
    • Carl Robinson,
    • Karen F. Steward,
    • Katy S. Webb,
    • Romain Paillot,
    • Julian Parkhill,
    • Matthew T.G. Holden,
    • and Andrew S. Waller
    Genome Res. September 2015 25: 1360-1371; Published in Advance July 9, 2015, doi:10.1101/gr.189803.115
    ...diversity and mechanisms underlying the evolution of S. equi as a host-restricted pathogen remain poorly understood. Here, we define the global population structure of this important pathogen and reveal a population replacement in the late 19th or early 20th Century. Our data reveal a dynamic that continues...
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  4. Method: Microbial strain-level population structure and genetic diversity from metagenomes
    • Duy Tin Truong,
    • Adrian Tett,
    • Edoardo Pasolli,
    • Curtis Huttenhower,
    • and Nicola Segata
    Genome Res. April 2017 27: 626-638; Published in Advance February 6, 2017, doi:10.1101/gr.216242.116
    ...of Streptococcus pneumoniae (Kilian et al. 2008) or Staphylococcus aureus (Holden et al. 2013). More broadly, the ability to profile strains directly frommetas is a key step toward a systems-level understanding of how members of the human microbiome interact with host physiology. Epidemiology and comparative...
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