Searching journal content for articles similar to Herrgård et al. 13 (11): 2423.

Displaying results 1-10 of 14
For checked items
  1. ...Matthew J. Rossi, William K.M. Lai and B. Franklin Pugh Center for Eukaryotic Gene Regulation, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA Corresponding author: bfp2@psu.eduAbstractGeneral regulatory factors (GRFs...
  2. .... 2003 . Experimental determination and system level analysis of essential genes in Escherichia coli MG1655. J. Bacteriol. 185 : 5673 -5684. ↵ Herrgard, M.J., Covert, M.W., and Palsson, B.Ø. 2003 . Reconciling gene expression data with known -scale regulatory network structures. Genome Res. 13 : 2423...
  3. ...dynamics in controlling gene expression, allowing for the 35 precise coordination of cellular functions. 36 37 INTRODUCTION 38 Gene expression is regulated at many levels in mammalian cells. Transcription initiation 39 is directed by epigenetic marks allowing regulatory DNA elements to be accessible to 40...
    OPEN ACCESS ARTICLEACCEPTED MANUSCRIPT
  4. ...of common developmental origin. Beta-cells selectively lack PcG repression in a neural regulatory program We next attempted to reconcile the paradox that in beta-cells a H3K27me3 repression signature shared with endoderm tissues is associated with a neural-like gene activity profile. We hypothesized...
  5. ...based on commonalities and differences in -wide expression patterns, reconstruct the heterogeneous composition of cell populations in tumors and their microenvironment, and unveil regulatory programs that govern the dynamic changes in gene expression along developmental trajectories.One of the most...
  6. ...). Nucleosomes influence the expression of a huge fraction of yeast genes (Wyrick et al. 1999) and the precise positioning of nucleosomes relative to underlying DNA, controls access to protein-binding sites, and thereby affects regulatory programs (Stunkel et al. 1997; Lomvardas and Thanos 2002; Lam et al. 2008...
  7. .... 2000 ; Ravasz et al. 2002 ; Ibarra et al. 2003 ; Almaas et al. 2004 , 2005 ). Control of metabolic activity can be studied by overlaying a transcriptional regulatory network in which edges represent regulatory interactions from transcription factors (TFs) to target genes. Data for the best...
  8. ...results show that studying FMR1 at multiple regulatory levels through our network-based approach can identify components of important cellular functions regulated by FMR1 in human neural cells. These network clusters and gene hubs validate some of the animal studies and point to novel functional targets...
  9. ...propose that differential accessibility is a signature of patterning cis-regulatory elements in the Drosophila blastoderm and discuss potential mechanisms by which accessibility of enhancers may be modulated by activator and repressor TFs.Embryonic development is controlled by gene regulatory networks...
  10. ...to a major wave, in which many more genes are activated (Tadros and Lipshitz 2009).The onset of activation takes place in a unique regulatory paradigm in which some genes must be activated in the context of an otherwise quiescent . For animals whose embryos undergo external development, such as zebrafish...
For checked items

Preprint Server