Searching journal content for articles similar to Henikoff et al. 19 (3): 460.

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  1. ....Overall, this study covers both the development of a cost-efficient strategy for generating spatial epigenomic maps on tissue sections and a bioinformatics strategy for a pioneer integrative effort in spatial chromatin-state profiling, essential for the field of “spatial omics,” anticipating the need for this type...
  2. ...and the comprehensive understanding of its deposition mechanism, relatively little is known about the function of H2AZ on the promoters on which it resides.Nucleosome occupancies are determined not only by chromatin remodeling enzymes but also by the intrinsic physical stability of nucleosomes. Features such as high AT...
  3. ...Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling Florian A. Steiner 1 , Paul B. Talbert 1 , Sivakanthan Kasinathan 1 , Roger B. Deal 1 and Steven Henikoff 1 , 2 , 3...
  4. ...://stability.matticklab.com/. Genome-wide analysis of lncRNA stability Genome Research 889 www..org sense transcripts were also more stable than head-to-head bidirectional transcripts (P < 0.05). Hierarchical clustering of lncRNA stability profiles supported this result. The most stable classes (intergenic, cis-antisense, tail...
  5. ...of specific genomic regions into these large ribonucleoprotein (RNP) complexes critically contributes to higher-order functional chromatin organization, such regions remain ill-defined. We have developed the high-salt–recovered sequences-sequencing (HRS-seq) method, a straightforward -wide approach whereby we...
  6. ...importance in regulating gene expression. We test this hypothesis using a restriction enzyme as a probe of chromatin structure and as a proxy for transcription factors. We measured the digestion rate and the fraction of accessible DNA at almost all genomic AluI sites in budding yeast and mouse liver nuclei...
  7. ...Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding A. Gordon Robertson 1 , 4 , Mikhail Bilenky 1 , 4 , Angela Tam 1 , Yongjun Zhao 1 , Thomas Zeng 1 , Nina Thiessen 1...
  8. ...Structured nucleosome fingerprints enable high-resolution mapping of chromatin architecture within regulatory regions Alicia N. Schep 1 , Jason D. Buenrostro 1 , Sarah K. Denny 2 , Katja Schwartz 1 , Gavin Sherlock 1 and William J...
  9. ...and modifications in regulating the DNA replication program. Genome-wide replication timing and early origins of replication are correlated with a variety of activating chromatin marks. Similarly, we find that ORC-binding sites are enriched for a subset of these chromatin marks as well as additional DNA...
  10. ...associated with regulatory proteins is a pronounced sensitivity to DNase I digestion. We generated genome-wide high-resolution maps of DNase I hypersensitive (DH) sites from both seedling and callus tissues of rice ( Oryza sativa ). Approximately 25% of the DH sites from both tissues were found in putative...
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