Searching journal content for articles similar to Hedges et al. 14 (6): 1068.

Displaying results 1-10 of 24
For checked items
  1. ...or heterogeneity that eliminates its activity. Thus, even though certain characteristics between old and young Alu subfamily members may look similar, it may be that all of the features necessary for activity are present only among a small group of the very youngest elements, those for which selection has not had...
  2. ...subfamilies ( Wang et al. 2006 ). Given the range of activity levels observed among Alu Y subfamilies, the diagnostic base changes that define these subfamilies appear to have affected the mobilization efficiencies of these elements. Overall, our data indicate that the subfamily status of a given Alu copy...
  3. ...also been used to clarify relationships among New World monkeys (NWM), Old World monkeys (OWM), and the human–chimpanzee–gorilla trichotomy (Salem et al. 2003; Ray and Batzer 2005; Ray et al. 2005; Xing et al. 2005). Alu elements in human lineage have been extensively characterized (Batzer...
  4. ...synthetic mammalian retrotransposon. Nature 429 : 314 –318. ↵ Hedges, D.J., Callinan, P.A., Cordaux, R., Xing, J., Barnes, E., and Batzer, M.A. 2004 . Differential Alu mobilization and polymorphism among the human and chimpanzee lineages. Genome Res. 14 : 1068 –1075. ↵ Jurka, J. 1993 . A new subfamily...
  5. ..., chimpanzee, and orangutan were likely acquired due to insertion of TEs ‘‘upon arrival’’ (12,794 out of 35,224 loci) (Fig. 4), with approximately equal contribution of Alus and L1s (6521 and 6273 loci, respectively). Additionally, among microsatellite births and deaths occurring in the human, chimpanzee...
  6. ...distribution of the 43 Alu insertion polymorphisms is skewed toward low insertion frequencies, in agreement with their absence in the HGP reference (Fig. 2). Mobile element-mediated insertions Among the 706 insertion events, 650 are HuRef-specific retrotransposon insertions, including 584 Alu, 52 L1, and 14...
  7. ...., Xing, J., Barnes, E., and Batzer, M.A. 2004 . Differential Alu mobilization and polymorphism among the human and chimpanzee lineages. Genome Res. 14 : 1068 -1075. ↵ Helleday, T. 2003 . Pathways for mitotic homologous recombination in mammalian cells. Mutat. Res. 532 : 103 -115. ↵ Higgins, D...
  8. ...( Arcot et al. 1996 ), although a few Ya5 Alu family members have been found in chimpanzees (for review, see Deininger and Batzer 1995 ). In parallel, a second subfamily that is an independent derivative of the Y lineage of Alu sequences, termed Yb8, has also expanded to ∼500 copies within the human...
  9. ...of tandem repeats (VNTR)-Alu (SVAs). ERVs and LINEs encode the reverse transcriptase and endonuclease activities necessary for their retrotransposition, whereas the nonautonomous SINE and SVA elements rely on LINE proteins for spreading. Due respectively to internal recombination and abortive...
  10. ...(A) and 79 novel Alu subfamilies (B) that were identified using interior sequence changes were analyzed for sharing among the 1000 Genomes Project nonadmixed continental populations. Plotted are: (top) log10 total sites in each subfamily; (bottom) proportion of sites shared among all continental...
For checked items

Preprint Server