Searching journal content for articles similar to He et al. 17 (10): 000.

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  1. Method: Prediction and characterization of noncoding RNAs in C. elegans by integrating conservation, secondary structure, and high-throughput sequencing and array data
    • Zhi John Lu,
    • Kevin Y. Yip,
    • Guilin Wang,
    • Chong Shou,
    • LaDeana W. Hillier,
    • Ekta Khurana,
    • Ashish Agarwal,
    • Raymond Auerbach,
    • Joel Rozowsky,
    • Chao Cheng,
    • Masaomi Kato,
    • David M. Miller,
    • Frank Slack,
    • Michael Snyder,
    • Robert H. Waterston,
    • Valerie Reinke,
    • and Mark B. Gerstein
    Genome Res. February 2011 21: 276-285; Published in Advance December 22, 2010, doi:10.1101/gr.110189.110
    .... Abstract We present an integrative machine learning method, incRNA , for whole-genome identification of noncoding RNAs (ncRNAs). It combines a large amount of expression data, RNA secondary-structure stability, and evolutionary conservation at the protein and nucleic-acid level. Using the incRNA model...
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  2. Resource: A spatial and temporal map of C. elegans gene expression
    • W. Clay Spencer,
    • Georg Zeller,
    • Joseph D. Watson,
    • Stefan R. Henz,
    • Kathie L. Watkins,
    • Rebecca D. McWhirter,
    • Sarah Petersen,
    • Vipin T. Sreedharan,
    • Christian Widmer,
    • Jeanyoung Jo,
    • Valerie Reinke,
    • Lisa Petrella,
    • Susan Strome,
    • Stephen E. Von Stetina,
    • Menachem Katz,
    • Shai Shaham,
    • Gunnar Rätsch,
    • and David M. Miller III
    Genome Res. February 2011 21: 325-341; Published in Advance December 22, 2010, doi:10.1101/gr.114595.110
    ...specific embryonic cells and Figure 1. Strategies for generating tiling array data sets from specific C. elegans cells in embryos and larvae and from whole animals at defined developmental stages. (A) In the MAPCeL (Micro-array Profiling of C. elegans Cells) method, embryos are isolated from gravid adults...
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  3. PERSPECTIVE: Genomics in C. elegans: So many genes, such a little worm
    • LaDeana W. Hillier,
    • Alan Coulson,
    • John I. Murray,
    • Zhirong Bao,
    • John E. Sulston,
    • and Robert H. Waterston
    Genome Res. December 2005 15: 1651-1660; doi:10.1101/gr.3729105
    ...of these regions in large insert clone libraries, we turned to a strategy of directly subcloning and shotgunsequencing a restriction fragment from whole genomic DNA for these internal gaps and the uncloned telomere from Chromosome II right. The regions containing the internal gaps and the remaining telomere were...
  4. PERSPECTIVE: Drosophila melanogaster: A case study of a model genomic sequence and its consequences
    • Michael Ashburner and
    • Casey M. Bergman
    Genome Res. December 2005 15: 1661-1667; doi:10.1101/gr.3726705
    ...and annotation of the Drosophila melanogaster genome, first published in 2000 through collaboration between Celera Genomics and the Drosophila Genome Projects, has provided a number of important contributions to genome research. By demonstrating the utility of methods such as whole-genome shotgun sequencing...
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