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Research: Frac-seq reveals isoform-specific recruitment to polyribosomes
- Timothy Sterne-Weiler,
- Rocio Teresa Martinez-Nunez,
- Jonathan M. Howard,
- Ivan Cvitovik,
- Sol Katzman,
- Muhammad A. Tariq,
- Nader Pourmand,
- and Jeremy R. Sanford
Genome Res. October 2013 23: 1615-1623; Published in Advance June 19, 2013, doi:10.1101/gr.148585.112
.... Pre-mRNA splicing: Where and when in the nucleus. Trends Cell Biol 21: 336–343. Hausser J, Syed AP, Bilen B, Zavolan M. 2013. Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation. Genome Res 23: 604–615. Hoskins AA, Moore MJ. 2012. The spliceosome...
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Research: Exonic splice regulation imposes strong selection at synonymous sites
- Rosina Savisaar and
- Laurence D. Hurst
Genome Res. October 2018 28: 1442-1454; Published in Advance August 24, 2018, doi:10.1101/gr.233999.117
...) might primarily act as a slight modifier of codon usage bias. In the latter, mutations that disrupt ESEs are likely to have large fitness and, potentially, clinical effects. To distinguish between these scenarios, we used several different methods to determine the distribution of selection coefficients...
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