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Resource: Small RNA expression and miRNA modification dynamics in human oocytes and early embryos
- Pauliina Paloviita,
- Christel Hydén-Granskog,
- Dawit A. Yohannes,
- Priit Paluoja,
- Juha Kere,
- Juha S. Tapanainen,
- Kaarel Krjutškov,
- Timo Tuuri,
- Urmo Võsa,
- and Sanna Vuoristo
Genome Res. August 2021 31: 1474-1485; doi:10.1101/gr.268193.120
...elucidating the dynamics of sRNA expression and miRNA modification along a continuous trajectory of early human development and provides a valuable data set for in-depth interpretative analyses.Mammalian oocytes and embryos express three major classes of small noncoding RNAs (sRNAs): Piwi-interacting RNAs (piRNAs...
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Letter: Abundant and dynamically expressed miRNAs, piRNAs, and other small RNAs in the vertebrate Xenopus tropicalis
- Javier Armisen,
- Michael J. Gilchrist,
- Anna Wilczynska,
- Nancy Standart,
- and Eric A. Miska
Genome Res. October 2009 19: 1766-1775; Published in Advance July 23, 2009, doi:10.1101/gr.093054.109
...where both strands are transcribed. Like miRNAs, endosiRNAs interact with Argonaute proteins. endo-siRNAs likely have roles in silencing of transposable elements or pseudogenes (Okamura et al. 2008). A third class of 25–30 nt RNAs has been identified in Drosophila, zebrafish, mice, rats, anemones...

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