Searching journal content for articles similar to Hanna et al. 26 (6): 756.

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  1. Research: Tracing human stem cell lineage during development using DNA methylation
    • Lucas A. Salas,
    • John K. Wiencke,
    • Devin C. Koestler,
    • Ze Zhang,
    • Brock C. Christensen,
    • and Karl T. Kelsey
    Genome Res. September 2018 28: 1285-1295; Published in Advance August 2, 2018, doi:10.1101/gr.233213.117
    ..., USA ↵8 These authors contributed equally to this work. ↵9 These authors contributed equally to this work. Corresponding author: john.wiencke@ucsf.eduAbstractStem cell maturation is a fundamental, yet poorly understood aspect of human development. We devised a DNA methylation signature deeply...
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  2. Review: The superpowers of imprinting control regions
    • Bertille Montibus,
    • Franck Court,
    • and Philippe Arnaud
    Genome Res. January 2026 36: 1-19; Published in Advance December 10, 2025, doi:10.1101/gr.281215.125
    ...allele-specific gene expression across large imprinted domains. In this review, we highlight the features that define ICRs as a distinct class of cis-regulatory regions, from their ability to maintain germline-inherited DNA methylation to their multifunctional roles in transcriptional control. For each...
  3. Review: Artificial intelligence and machine learning in cell-free-DNA-based diagnostics
    • W.H. Adrian Tsui,
    • Spencer C. Ding,
    • Peiyong Jiang,
    • and Y.M. Dennis Lo
    Genome Res. January 2025 35: 1-19; doi:10.1101/gr.278413.123
    ...and is applied to the prediction of cytosine methylation status. The methylation probability for the CpG sites, ranging from zero to one, is computed using a sigmoid function at the output layer. (Right) Selected clinical applications of the HK model: (1) deducing the placenta-derived cfDNA by the methylation...
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  4. Research: Genetic, epigenetic, and environmental mechanisms govern allele-specific gene expression
    • Celine L. St. Pierre,
    • Juan F. Macias-Velasco,
    • Jessica P. Wayhart,
    • Li Yin,
    • Clay F. Semenkovich,
    • and Heather A. Lawson
    Genome Res. June 2022 32: 1042-1057; Published in Advance May 2, 2022, doi:10.1101/gr.276193.121
    ...-of-origin-dependent ASE in which one parent's allele is silenced via selective epigenetic marks, such as DNA methylation and histone modifications (Umlauf et al. 2004; Barlow and Bartolomei 2014; Inoue et al. 2017). Known imprinted genes compose ∼1% of the human and mouse s, yet play important roles in development...
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  1. April 2026, 36 (4)
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