Searching journal content for articles similar to Han et al. 31 (11): 2008.

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  1. Research: Analysis of a cell-free DNA–based cancer screening cohort links fragmentomic profiles, nuclease levels, and plasma DNA concentrations
    • Yasine Malki,
    • Guannan Kang,
    • W.K. Jacky Lam,
    • Qing Zhou,
    • Suk Hang Cheng,
    • Peter P.H. Cheung,
    • Jinyue Bai,
    • Ming Lok Chan,
    • Chui Ting Lee,
    • Wenlei Peng,
    • Yiqiong Zhang,
    • Wanxia Gai,
    • Winsome W.S. Wong,
    • Mary-Jane L. Ma,
    • Wenshuo Li,
    • Xinzhou Xu,
    • Zhuoran Gao,
    • Irene O.L. Tse,
    • Huimin Shang,
    • L.Y. Lois Choy,
    • Peiyong Jiang,
    • K.C. Allen Chan,
    • and Y.M. Dennis Lo
    Genome Res. January 2025 35: 31-42; Published in Advance November 27, 2024, doi:10.1101/gr.279667.124
    ...Analysis of a cell-free DNA–based cancer screening cohort links fragmentomic profiles, nuclease levels, and plasma DNA concentrations Yasine Malki1,2,3,5, Guannan Kang1,2,3,5, W.K. Jacky Lam1,2,3,4,5, Qing Zhou1,2,3, Suk Hang Cheng1,2,3, Peter P.H. Cheung2,3, Jinyue Bai1,2,3, Ming Lok Chan2,3, Chui...
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  2. Review: Artificial intelligence and machine learning in cell-free-DNA-based diagnostics
    • W.H. Adrian Tsui,
    • Spencer C. Ding,
    • Peiyong Jiang,
    • and Y.M. Dennis Lo
    Genome Res. January 2025 35: 1-19; doi:10.1101/gr.278413.123
    ...@cuhk.edu.hkAbstractThe discovery of circulating fetal and tumor cell-free DNA (cfDNA) molecules in plasma has opened up tremendous opportunities in noninvasive diagnostics such as the detection of fetal chromosomal aneuploidies and cancers and in posttransplantation monitoring. The advent of high-throughput sequencing...
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  3. Research: Genomic origin, fragmentomics, and transcriptional properties of long cell-free DNA molecules in human plasma
    • Huiwen Che,
    • Peiyong Jiang,
    • L.Y. Lois Choy,
    • Suk Hang Cheng,
    • Wenlei Peng,
    • Rebecca W.Y. Chan,
    • Jing Liu,
    • Qing Zhou,
    • W.K. Jacky Lam,
    • Stephanie C.Y. Yu,
    • So Ling Lau,
    • Tak Y. Leung,
    • John Wong,
    • Vincent Wai-Sun Wong,
    • Grace L.H. Wong,
    • Stephen L. Chan,
    • K.C. Allen Chan,
    • and Y.M. Dennis Lo
    Genome Res. February 2024 34: 189-200; Published in Advance February 26, 2024, doi:10.1101/gr.278556.123
    ...-Mayouf et al. 2011). Long cfDNA that are generated by DFFB might have potential immunomodulatory effects to the innate immune responses.Prior studies systematically profiled plasma DNA end motifs using mice of different genotypes and found altered end motif frequencies in nuclease-deficient mice (Serpas et...
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