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  1. ...the consequences of centromere breakage on wheat genomic architecture, we analyzed the CS ditelosomic (CSDt) lines from homoeologous groups 1, 6, and 7 chromosomes. Cytogenetic analysis confirmed the presence of telosomic chromosomes carrying either the short or long arm (Supplemental Fig. S1). Telomeric signals...
  2. ...ChIP-seq signals (Fig. 3B), as highlighted with DMCR1A, PRTOP_A, and PRTOP_B on the right arm of Chromosome 2 (Fig. 3C). We next determined RNA class, genomic origin, and relative abundance for each CHARR. The largest RNA class corresponds to LTR (n = 47) and the second to LINE repeats (n = 19) (Fig...
  3. ...V. , Archidiacono N. , Rocchi M. , Scott C. , et al. ( 2000 ) Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10q. Hum. Mol. Genet. 9 : 2029 – 2042 . ↵ Horvath J.E. , Schwartz S. , Eichler E.E. ( 2000a ) The mosaic...
  4. ...isolated and sequenced a 554-kb genomic segment from the human Y chromosome that contains a 450-kb euchromatic island hidden between satellite 3 sequence, adjacent to the centromere on the long arm of the chromosome. Analysis of the Y-specific pericentromeric sequence revealed that it is almost entirely...
  5. ...polymorphic sequences within the short arm of human chromosome 21. Genome Res 17: 1690–1696. ↵ Mais C, Wright JE, Prieto JL, Raggett SL, McStay B Mais C, Wright JE, Prieto JL, Raggett SL, McStay B. 2005. UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery. Genes...
  6. ...of the heterochromatic regions. We describe here an initial sequence of 1.1 Mb of the short arm of human chromosome 21 (HSA21p), estimated to be 10% of 21p. This region contains extensive euchromatic-like sequence and includes on average one transcript every 100 kb. These transcripts show multiple inter...
  7. ...implied a model of pericentromeric sequence organization on this chromosome arm consisting of two distinct domains: (1) a proximal domain that is satellite rich, transcript poor, and prone to interchromosomal duplication; and (2) a distal domain that is satellite poor and prone to intrachromosomal...
  8. ...with related copies on both the q and p arms of human chromosome 5, and show at least 90% nucleic acid sequence identity to functional genes located elsewhere in the . A preliminary PCR analysis of the DNA of different primate species revealed that those sequences have emerged during the last 35 million years...
  9. ...) was largely similar to the 4q35 “SD-amplicon” reported by Ballarati et al. (2002) . Homology with short arms of acrocentric chromosomes and the presence of BSR and LSau satellites suggest similarity to the low-copy sequences, characteristic for rDNA boundary, described by Bodega et al. (2006) . On this basis...
  10. ...for the juxtacentromeric (or pericentromeric) region of the long arm of human chromosome 21. We demonstrate that most HapMap data are reliable within this region. We show that high linkage disequilibrium between pairs of SNPs extends 719–737 kb from the centromeric α-satellite. In the same region we find a peak of histone...
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