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  1. ...multiple divergent species (Summerer 2009). This problem is exacerbated for museum specimens, where DNA quality varies greatly between samples and contamination levels are often high (Millar et al. 2008). Generation of whole sequences for museum specimens, or even complete mitochondrial DNA (mtDNA...
  2. ...of research to advance the study of archaic introgression.Prior to high-throughput sequencing, whether archaic humans (e.g., Neanderthals and Denisovans) contributed to the modern human gene pool was hotly debated (Stringer and Andrews 1988; Wolpoff et al. 1994; Stringer 2022). Early analyses of mitochondrial...
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  3. ...SNVs with a consensus deleteriousness score, Condel. Am J Hum Genet 88: 440–449. Gunnarsdottir ED, Li M, Bauchet M, Finstermeier K, Stoneking M. 2011. High-throughput sequencing of complete human mtDNA s from the Philippines. Genome Res 21: 1–11. Hammer MF. 1995. A recent common ancestry for human Y...
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