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  1. ...deletion of the short arm of chromosome 5. Clin. Genet. 34 : 219 – 223 . ↵ Buckler A.J. , Chang D.D. , Graw S.L. , Brook J.D. , Haber D.A. , Sharp P.A. , Housman D.E. ( 1991 ) Exon amplification: A strategy to isolate mammalian genes based on RNA splicing. Proc. Natl. Acad. Sci. 88 : 4005 – 4009 . ↵ Church...
  2. ...be variations in the proteins and RNAs that interact with cis -regulatory sequences and so are genetically in trans ( Fig. 1 ). As the gene associated with each mRNA expression trait can be physically mapped onto the , the mechanism ( cis -acting or trans -acting) by which an eQTL influences an expression trait...
  3. ...androgen receptor RNA in the Tfm mouse. Mol. Endocrinol. 5: 573–581. Chin, L.S., L. Li, A. Ferreira, K.S. Kosik, and P. Greengard. 1995. Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice. Proc. Natl. Acad. Sci. 92: 9230–9234. Cunliffe, P. 1999...
  4. ...for the identification of CpG islands as defined by Gardiner-Garden and Frommer (1987) . Mutation Analysis of the NEFA Gene Total RNA was isolated from lymphoblast cell cultures of affected and nonaffected individuals using the RNeasy minikit (Qiagen). Following treatment with RNase-free DNase (GIBCO BRL), first...
  5. .... , Chua S.C. , Jr., , Leibel, R.L. , Weissenbach, J. , Friedman. J.M. Green, E.D., Maffei, M. Braden, V.V. Proenca, R. DeSilva, U. Zhang, Y. Chua S.C. , Jr., Leibel, R.L. Weissenbach, J. and Friedman. J.M. 1995b . The human Obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic...
  6. ....L. Rosato, E.L. Colberg, J. and Caro. J.F. 1995 . Evidence aganist either a premature stop codon or the absence of obese gene mRNA in human obesity. J. Clin. Invest. 95 : 2720 – 2728 . Considine, R.V., , Sinha, M.K. , Heiman, M.L. , Kriauciunas, A. , Stephens, T.W. , Myce, M.R. , Ohannesian, J.P. , Marco, C...
  7. ...centromere, opposite that for SNRPN ( Buiting et al. 1993 ). View larger version: In this window In a new window Figure 3. Northern analysis of UBE3A gene expression. Hybridization of UBE3A and control GAP3D cDNA probes to a Northern filter (Clontech) containing 2 μg poly(A)+ RNA per lane is shown...
  8. ..., such as lariats, fusion genes, and tandem duplications. These methods have been extensively compared using benchmark data sets (Hansen et al. 2016; Zeng et al. 2017; Hansen 2018). The identified circRNAs and their expression information are cataloged in several databases (Glažar et al. 2014; Chen et al. 2016...
  9. ..., albeit a conservative one, as to where it might be headed. Genome sequencing, database development, expression arrays, and SNP maps with automated genotyping will obviously become staples of our genomic toolbox, probably before our current generation of graduate students leaves our laboratories. RNA...
  10. ...apolipoprotein Apoa-1/Apoc-3 gene locus: Genomic, mRNA, and protein sequences with comparisons to other species. Genomics 14 : 1081 – 1088 . ↵ Jones C.T. , Morrice D.R. , Paton I.R. , Burt D.W. ( 1997 ) Gene homologs on human chromosome 15q21–q26 and a chicken microchromosome identify a new conserved segment...
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