Searching journal content for articles similar to Gordon et al. 22 (8): 1395.

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  1. Research: Genetic and environmental exposures constrain epigenetic drift over the human life course
    • Sonia Shah,
    • Allan F. McRae,
    • Riccardo E. Marioni,
    • Sarah E. Harris,
    • Jude Gibson,
    • Anjali K. Henders,
    • Paul Redmond,
    • Simon R. Cox,
    • Alison Pattie,
    • Janie Corley,
    • Lee Murphy,
    • Nicholas G. Martin,
    • Grant W. Montgomery,
    • John M. Starr,
    • Naomi R. Wray,
    • Ian J. Deary,
    • and Peter M. Visscher
    Genome Res. November 2014 24: 1725-1733; Published in Advance September 23, 2014, doi:10.1101/gr.176933.114
    ...of gene expression. DNAm is dynamic, influenced by both environmental and genetic factors. Epigenetic drift is the divergence of the epigenome as a function of age due to stochastic changes in methylation. Here we show that epigenetic drift may be constrained at many CpGs across the human genome by DNA...
  2. Research: The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes
    • Ai Ling Teh,
    • Hong Pan,
    • Li Chen,
    • Mei-Lyn Ong,
    • Shaillay Dogra,
    • Johnny Wong,
    • Julia L. MacIsaac,
    • Sarah M. Mah,
    • Lisa M. McEwen,
    • Seang-Mei Saw,
    • Keith M. Godfrey,
    • Yap-Seng Chong,
    • Kenneth Kwek,
    • Chee-Keong Kwoh,
    • Shu-E. Soh,
    • Mary F.F. Chong,
    • Sheila Barton,
    • Neerja Karnani,
    • Clara Y. Cheong,
    • Jan Paul Buschdorf,
    • Walter Stünkel,
    • Michael S. Kobor,
    • Michael J. Meaney,
    • Peter D. Gluckman,
    • and Joanna D. Holbrook
    Genome Res. July 2014 24: 1064-1074; Published in Advance April 7, 2014, doi:10.1101/gr.171439.113
    ...methylation marks are specified by sequence context in cis (Brandeis et al. 1994; Lienert et al. 2011), precluding exclusive environmental regulation. In humans, interindividual variation in DNA methylation could be wholly or in part a consequence of nucleotide polymorphism, as local genetic variants...
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  3. Research: Reprogramming of the human intestinal epigenome by surgical tissue transposition
    • Fides D. Lay,
    • Timothy J. Triche, Jr.,
    • Yvonne C. Tsai,
    • Sheng-Fang Su,
    • Sue Ellen Martin,
    • Siamak Daneshmand,
    • Eila C. Skinner,
    • Gangning Liang,
    • Yoshitomo Chihara,
    • and Peter A. Jones
    Genome Res. April 2014 24: 545-553; Published in Advance February 10, 2014, doi:10.1101/gr.166439.113
    ..., Cruickshank MN, Conneely KN, Smith AK, et al. 2012. Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence. Genome Res 22: 1395–1406. Halley-Stott RP, Gurdon JB. 2013. Epigenetic memory...
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