Searching journal content for articles similar to González-Neira et al. 16 (3): 323.

Displaying results 1-3 of 3
For checked items
  1. ...that are representative of the target populations to be imputed.While it has been shown that tagging SNPs identified from the HapMap are expected to be portable across other non-African populations (de Bakker et al. 2006; Conrad et al. 2006; Huang et al. 2009), imputation performance is expected to be optimized if local...
  2. ...; Servin and Stephens 2007). Central to the selection of tag SNPs and the use of HapMap populations as reference panels in imputation is the assumption that patterns of LD are similar between the target and HapMap populations (Clark and Li 2007; Marchini et al. 2007). Population differences in LD structure...
  3. ...genomic region and enables the design of cost-efficient genetic association studies. Such SNPs are commonly designated as tagging SNPs or tSNPs. This notion motivated the HapMap project, which in phase I has released a public database of 1,000,000 SNPs, typed in four populations from three geographic...
For checked items

Preprint Server