Searching journal content for articles similar to Gonçalves et al. 10 (5): 672.

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  1. ...to document the likely events from processing to RT priming and genomic integration, and allowed us to propose a potential mechanism of tailless retropseudogene generation. RESULTS AND DISCUSSION Search Results and Species Distribution Using a computational, -wide search strategy for extracting preferentially...
  2. ...and comparing inserted elements among various s. The suite comprises two user-friendly web-based modules. The 2-way module generates pairwise whole- alignments of target and query species. The resulting coordinates of blocks (matching sequences) and gaps (missing sequences) from multiple 2-ways...
  3. ...L1 elements, 47 long terminal repeats (LTRs), and 20 retropseudogenes. However, the short interspersed elements (SINEs) frequently used as phylogenetic markers within mammalian orders did not cross order boundaries in laurasiatherians and were therefore not suitable for the superorder Laurasiatheria...
  4. ...by explaining the general prevalence of their testis expression, and a parsimonious solution for new alleles to avoid being lost by genetic drift or pseudogenization.New gene origination is thought to play a major role in phenotypic evolution (Kaessmann 2010; Chen et al. 2013). New genes may originate from...
  5. ...reconstruction of the “life history” of mammalian retrogenes highlights retroposition as a general model for understanding new gene birth and functional evolution. [Supplemental material is available for this article.] In addition tomutations that alter sequences or activities of preexisting genes (Necsulea...
  6. ...housekeeping function implies high genomic conservation. However, in nematodes, we recently found an extraordinary degree of plasticity in the generation of snoRNA paralogs as well as in the selection of their modified targets ( Zemann et al. 2006 ). In a process termed cis -duplication, we found that some sno...
  7. ...). Thus, these RNASE1 duplications represent striking cases of convergent molecular evolution. They were likely facilitated by the frequent occurrence of segmental duplication, which allows similar duplication events that are highly beneficial to be repeatedly fixed during evolution. More generally...
  8. ...; Wen et al. 2011; Pei et al. 2012). For instance, some transcribed processed pseudogenes express antisense transcripts which pair to the mRNA of their parent genes, generating a natural endogenous small interfering RNA and, consequently, reducing the expression of the parent gene (Tam et al. 2008...
  9. .... ↵ Goncalves I. , Duret L. , Mouchiroud D. ( 2000 ) Nature and structure of human genes that generate retropseudogenes. Genome Res. 10 : 672 – 678 . ↵ Harrison P.M. , Hegyi H. , Balasubramanian S. , Luscombe N.M. , Bertone P. , Echols N. , Johnson T. , Gerstein M. ( 2002 ) Molecular fossils in the human...
  10. ...2EST: A BLAST2 server for searching expressed sequence tag (EST) databases with eukaryotic gene-sized queries. Nucleic Acids Res. 29 : 1272 -1277. ↵ Goncalves, I., Duret, L., and Mouchiroud, D. 2000 . Nature and structure of human genes that generate retropseudogenes. Genome Res. 10 : 672 -678...
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