Searching journal content for articles similar to Gervin et al. 21 (11): 1813.

Displaying results 1-10 of 24

For checked items

view abstracts
download to citation manager

Select this article
Research: Epigenetic drift score captures directional methylation variability and links aging to transcriptional, metabolic, and genetic alterations
- Xiu Fan,
- Qili Qian,
- Wenran Li,
- Tianzi Liu,
- Changqing Zeng,
- Peilin Jia,
- Huandong Lin,
- Xin Gao,
- Li Jin,
- Mingfeng Xia,
- Sijia Wang,
- and Fan Liu
Genome Res. October 2025 35: 2173-2188; Published in Advance August 1, 2025, doi:10.1101/gr.280155.124
...(Li and Tollefsbol 2016; López-Otín et al. 2023). Among these, DNA methylation drift has emerged as the most extensively characterized component of epigenetic aging. It is typified by increased variance in methylation levels at specific CpG sites—termed drift-CpGs—over chronological age...
OPEN ACCESS ARTICLE
Select this article
Resource: A DNA methylation fingerprint of 1628 human samples
- Agustin F. Fernandez,
- Yassen Assenov,
- Jose Ignacio Martin-Subero,
- Balazs Balint,
- Reiner Siebert,
- Hiroaki Taniguchi,
- Hiroyuki Yamamoto,
- Manuel Hidalgo,
- Aik-Choon Tan,
- Oliver Galm,
- Isidre Ferrer,
- Montse Sanchez-Cespedes,
- Alberto Villanueva,
- Javier Carmona,
- Jose V. Sanchez-Mut,
- Maria Berdasco,
- Victor Moreno,
- Gabriel Capella,
- David Monk,
- Esteban Ballestar,
- Santiago Ropero,
- Ramon Martinez,
- Marta Sanchez-Carbayo,
- Felipe Prosper,
- Xabier Agirre,
- Mario F. Fraga,
- Osvaldo Graña,
- Luis Perez-Jurado,
- Jaume Mora,
- Susana Puig,
- Jaime Prat,
- Lina Badimon,
- Annibale A. Puca,
- Stephen J. Meltzer,
- Thomas Lengauer,
- John Bridgewater,
- Christoph Bock,
- and Manel Esteller
Genome Res. February 2012 22: 407-419; Published in Advance May 25, 2011, doi:10.1101/gr.119867.110
...patients, it is noteworthy to consider that these samples were also previously analyzed using the same 1505 CpG array to search for DNA methylation differences between monozygotic twins (Javierre et al. 2010). Herein, they were studied in a more stringent manner because they were compared to a new large...
OPEN ACCESS ARTICLE
Select this article
Letter: Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
- Biola M. Javierre,
- Agustin F. Fernandez,
- Julia Richter,
- Fatima Al-Shahrour,
- J. Ignacio Martin-Subero,
- Javier Rodriguez-Ubreva,
- Maria Berdasco,
- Mario F. Fraga,
- Terrance P. O'Hanlon,
- Lisa G. Rider,
- Filipe V. Jacinto,
- F. Javier Lopez-Longo,
- Joaquin Dopazo,
- Marta Forn,
- Miguel A. Peinado,
- Luis Carreño,
- Amr H. Sawalha,
- John B. Harley,
- Reiner Siebert,
- Manel Esteller,
- Frederick W. Miller,
- and Esteban Ballestar
Genome Res. February 2010 20: 170-179; Published in Advance December 22, 2009, doi:10.1101/gr.100289.109
...Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus Biola M. Javierre 1 , Agustin F. Fernandez 2 , Julia Richter 3 , Fatima Al-Shahrour 4 , 5 , 6 , J. Ignacio Martin-Subero 3...
Select this article
Method: Quantifying the regulatory effect size of cis-acting genetic variation using allelic fold change
- Pejman Mohammadi,
- Stephane E. Castel,
- Andrew A. Brown,
- and Tuuli Lappalainen
Genome Res. November 2017 27: 1872-1884; Published in Advance October 11, 2017, doi:10.1101/gr.216747.116
..., and it is a valuable approach for investigating novel aspects of eQTL data sets. [Supplemental material is available for this article.] Noncoding genetic variation affecting gene regulation and other cellular phenotypes has a key role in phenotypic variation and disease susceptibility (Albert and Kruglyak 2015). One...
OPEN ACCESS ARTICLE
Select this article
Method: Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm
- Bo Zhang,
- Yan Zhou,
- Nan Lin,
- Rebecca F. Lowdon,
- Chibo Hong,
- Raman P. Nagarajan,
- Jeffrey B. Cheng,
- Daofeng Li,
- Michael Stevens,
- Hyung Joo Lee,
- Xiaoyun Xing,
- Jia Zhou,
- Vasavi Sundaram,
- GiNell Elliott,
- Junchen Gu,
- Taoping Shi,
- Philippe Gascard,
- Mahvash Sigaroudinia,
- Thea D. Tlsty,
- Theresa Kadlecek,
- Arthur Weiss,
- Henriette O’Geen,
- Peggy J. Farnham,
- Cécile L. Maire,
- Keith L. Ligon,
- Pamela A.F. Madden,
- Angela Tam,
- Richard Moore,
- Martin Hirst,
- Marco A. Marra,
- Baoxue Zhang,
- Joseph F. Costello,
- and Ting Wang
Genome Res. September 2013 23: 1522-1540; Published in Advance June 26, 2013, doi:10.1101/gr.156539.113
...; CpG and MRE-site content are fixed for any Genome Research 1523 www..org Discovering DNA methylation differences with M&M specific genomic region when SNP, mutation, or copy number differences are not considered.Whengenetic variation data is available for the sample, corrections can bemade to reflect...
OPEN ACCESS ARTICLE
Select this article
Research: Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence
- Lavinia Gordon,
- Jihoon E. Joo,
- Joseph E. Powell,
- Miina Ollikainen,
- Boris Novakovic,
- Xin Li,
- Roberta Andronikos,
- Mark N. Cruickshank,
- Karen N. Conneely,
- Alicia K. Smith,
- Reid S. Alisch,
- Ruth Morley,
- Peter M. Visscher,
- Jeffrey M. Craig,
- and Richard Saffery
Genome Res. August 2012 22: 1395-1406; Published in Advance July 16, 2012, doi:10.1101/gr.136598.111
...-scale DNA methylation profiling to measure the level of epigenetic variation present in three tissues from22MZ and 12DZ twin pairs collected at birth.We then estimated the within-pair variation of methylation profile generally and in the context of specific genomic features, and estimated...
Select this article
Letter: Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences
- Elmar Schilling,
- Carol El Chartouni,
- and Michael Rehli
Genome Res. November 2009 19: 2028-2035; Published in Advance August 17, 2009, doi:10.1101/gr.095562.109
.... Heritable rather than age-related environmental and stochastic factors dominate variation in DNAmethylation of the human IGF2/H19 locus. Hum Mol Genet 16: 547–554. Kaminsky ZA, Tang T, Wang SC, Ptak C, Oh GH, Wong AH, Feldcamp LA, Virtanen C, Halfvarson J, Tysk C, et al. 2009. DNA methylation profiles...
Select this article
Research: Locus-resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic development
- Patricia Gerdes,
- Dorothy Chan,
- Mischa Lundberg,
- Francisco J. Sanchez-Luque,
- Gabriela O. Bodea,
- Adam D. Ewing,
- Geoffrey J. Faulkner,
- and Sandra R. Richardson
Genome Res. September 2023 33: 1465-1481; Published in Advance October 5, 2023, doi:10.1101/gr.278003.123
...and epigenetic status, including DNA methylation of the monomeric units constituting young mouse L1 promoters. Locus-specific L1 methylation dynamics during development may therefore elucidate and explain spatiotemporal niches of endogenous retrotransposition but remain unresolved. Here, we interrogate...
OPEN ACCESS ARTICLE
Select this article
Research: Diverse environmental perturbations reveal the evolution and context-dependency of genetic effects on gene expression levels
- Amanda J. Lea,
- Julie Peng,
- and Julien F. Ayroles
Genome Res. October 2022 32: 1826-1839; Published in Advance October 13, 2022, doi:10.1101/gr.276430.121
...will be important for corroborating the patterns we see here. Finally, we did not generate environment-specific data on additional gene regulatory mechanisms such as DNA methylation, chromatin accessibility, or chromatin state. Although this work was beyond the scope of the present study, it is a key avenue...
OPEN ACCESS ARTICLE
Select this article
Research: Genetic and environmental exposures constrain epigenetic drift over the human life course
- Sonia Shah,
- Allan F. McRae,
- Riccardo E. Marioni,
- Sarah E. Harris,
- Jude Gibson,
- Anjali K. Henders,
- Paul Redmond,
- Simon R. Cox,
- Alison Pattie,
- Janie Corley,
- Lee Murphy,
- Nicholas G. Martin,
- Grant W. Montgomery,
- John M. Starr,
- Naomi R. Wray,
- Ian J. Deary,
- and Peter M. Visscher
Genome Res. November 2014 24: 1725-1733; Published in Advance September 23, 2014, doi:10.1101/gr.176933.114
...through either showingno variation in DNA methylation levels or through technical issues is 20%. This indicates that although our estimated proportion of repeatable results in LBC is downwardly biased by the presence of probes with technical issues or having no variation in DNA methylation...

For checked items

view abstracts
download to citation manager

Searching journal content for articles similar to Gervin et al. 21 (11): 1813.

Search Results

Modify Results

This search

Preprint Server

Current Issue

In This Issue

Citation format:
Results / page:
Results order: